NPPES file of Aug 9, 2026

Prisma Health Upstate

Prisma Health Upstate holds 105 active organization NPIs in the federal registry, with practice locations in 16 South Carolina cities. Each location can bill under its own NPI.

CMS NPPES registry, file of Aug 9, 2026 · legal names grouped after punctuation and "LLC" are removed · method · Verify with CMS →

Which NPI is yours?

Search the organization with your city to find the NPI for the location you visit or bill.

Find a location's NPI

Greenville has the most NPIs, 53

  1. Greenville53
  2. Seneca17
  3. Simpsonville5
  4. Clinton4
  5. Easley4
  6. Greer4
  7. Travelers Rest3
  8. Anderson2

Source: CMS NPPES monthly file of Aug 9, 2026, organization NPIs by practice city.

Most NPIs were issued in 2016 and 2023

Prisma Health Upstate NPIs by year issued2015: 1, 2016: 56, 2017: 0, 2018: 7, 2019: 6, 2020: 1, 2021: 8, 2022: 2, 2023: 17, 2024: 5, 2025: 2020406020152016201720182019202020212022202320242025561717618252
Prisma Health Upstate NPIs by year issued2015: 1, 2016: 56, 2017: 0, 2018: 7, 2019: 6, 2020: 1, 2021: 8, 2022: 2, 2023: 17, 2024: 5, 2025: 2020406020152016201720182019202020212022202320242025561717618252
Prisma Health Upstate NPIs by year issued2015: 1, 2016: 56, 2017: 0, 2018: 7, 2019: 6, 2020: 1, 2021: 8, 2022: 2, 2023: 17, 2024: 5, 2025: 202040602015201720192021202320252016: 561717618252

Source: CMS NPPES, enumeration dates.

56 NPIs were issued in 2016 alone, more than in any other year; none in 1 of the years between.

Greenville locations

The city with the most Prisma Health Upstate NPIs. The full list of all 105 follows.

NPILocationPrimary taxonomyIssued
1891148821701 GROVE RD, GreenvillePsychiatric HospitalJul 14, 2016
109316806429 N ACADEMY ST, GreenvilleMedically Fragile Infants and Children Day CareJul 14, 2016
12750864311025 VERDAE BLVD SUITE D, GreenvilleSleep Disorder Diagnostic Clinic/CenterJul 25, 2016
1609329861890 W FARIS RD SUITE 560, GreenvilleSleep Disorder Diagnostic Clinic/CenterJul 25, 2016
1225583115701 GROVE RD, GreenvilleRehabilitation HospitalAug 20, 2016
1316492218701 GROVE RD, GreenvilleClinic/CenterAug 20, 2016
1144775032200 PATEWOOD DR BUILDING A, GreenvilleGeneral Acute Care HospitalAug 20, 2016
1861947756100 AUGUSTA ST, GreenvilleComprehensive Outpatient Rehabilitation Facility (CORF)Aug 20, 2016
All 105 locations, by city
NPILocationPrimary taxonomyIssued
14075023134532 LIBERTY HWY, AndersonRural Health Clinic/CenterMar 1, 2022
13360394608 JUSTICE LN, AndersonRural Health Clinic/CenterJul 9, 2025
19023520082400 BOILING SPRINGS RD, Boiling SpringsGeneral Acute Care HospitalAug 29, 2016
1619423704450 OLD GREENVILLE HWY, ClemsonRural Health Clinic/CenterAug 29, 2016
1013698687450 OLD GREENVILLE HWY, ClemsonMulti-Specialty Clinic/CenterJul 27, 2023
1134512395210 S BROAD ST, ClintonRural Health Clinic/CenterMar 12, 2015
156891866222725 HIGHWAY 76 E MEDICAL OFFICE BUILDING 3RD FLOOR, ClintonGeneral Acute Care HospitalAug 29, 2016
124578636722725 HIGHWAY 76 E, ClintonGeneral Acute Care HospitalAug 29, 2016
1235819046210 S BROAD ST, ClintonMulti-Specialty Clinic/CenterJul 18, 2023
1851847974200 FLEETWOOD DR STE 200, EasleyGeneral Acute Care HospitalAug 29, 2016
1639656713200 FLEETWOOD DR, EasleyGeneral Acute Care HospitalJul 23, 2018
16699513641807A E MAIN ST, EasleyGeneral Acute Care HospitalAug 13, 2018
1760963243112 JOHN ST STE 104, EasleyGeneral Acute Care HospitalAug 23, 2018
1205414828200 N. NELSON DRIVE, Fountain InnRural Health Clinic/CenterApr 2, 2021
1164102927200 N NELSON DR, Fountain InnMulti-Specialty Clinic/CenterJul 18, 2023
17002397879100 HIGHWAY 14, Gray CourtRural Health Clinic/CenterJul 14, 2016
11944059699100 HIGHWAY 14, Gray CourtMulti-Specialty Clinic/CenterJul 18, 2023
1891148821701 GROVE RD, GreenvillePsychiatric HospitalJul 14, 2016
109316806429 N ACADEMY ST, GreenvilleMedically Fragile Infants and Children Day CareJul 14, 2016
12750864311025 VERDAE BLVD SUITE D, GreenvilleSleep Disorder Diagnostic Clinic/CenterJul 25, 2016
1609329861890 W FARIS RD SUITE 560, GreenvilleSleep Disorder Diagnostic Clinic/CenterJul 25, 2016
1225583115701 GROVE RD, GreenvilleRehabilitation HospitalAug 20, 2016
1316492218701 GROVE RD, GreenvilleClinic/CenterAug 20, 2016
1144775032200 PATEWOOD DR BUILDING A, GreenvilleGeneral Acute Care HospitalAug 20, 2016
1861947756100 AUGUSTA ST, GreenvilleComprehensive Outpatient Rehabilitation Facility (CORF)Aug 20, 2016
140730130232 STONEY POINT DR, GreenvillePACE Provider OrganizationAug 20, 2016
18518466615 W MAIN ST, GreenvilleGeneral Acute Care HospitalAug 22, 2016
14073012111120 GROVE RD, GreenvilleGeneral Acute Care HospitalAug 22, 2016
193265470413 EDGEWOOD DR, GreenvilleGeneral Acute Care HospitalAug 22, 2016
1689129496900 W FARIS RD, GreenvilleGeneral Acute Care HospitalAug 22, 2016
1033664909200 PATEWOOD DR SUITE C300, GreenvilleGeneral Acute Care HospitalAug 22, 2016
174073551310 QUEST DR, GreenvilleLand AmbulanceAug 22, 2016
1295280063701 GROVE RD, GreenvilleEmotionally Disturbed Childrens' Residential Treatment FacilityAug 22, 2016
1124574223200 PATEWOOD DR, GreenvilleGeneral Acute Care HospitalAug 29, 2016
1770039885701 GROVE RD, GreenvilleInfusion Therapy Clinic/CenterAug 29, 2016
196295806631 MEDICAL RIDGE DR, GreenvilleBirthing Clinic/CenterAug 29, 2016
143760553220 MEDICAL RIDGE DR, GreenvilleGeneral Acute Care HospitalAug 29, 2016
12356853301210 W FARIS RD, GreenvilleRadiology Clinic/CenterAug 29, 2016
1942756051701 GROVE RD, GreenvilleGeneral Acute Care HospitalAug 29, 2016
1114473212900 W FARIS RD, GreenvilleGeneral Acute Care HospitalAug 29, 2016
16598277563 BUTTERNUT DR SUITE B, GreenvilleGeneral Acute Care HospitalAug 29, 2016
13669984603 BUTTERNUT DR SUITE B4, GreenvilleGeneral Acute Care HospitalAug 29, 2016
139629140729 N ACADEMY ST, GreenvilleDevelopmental Disabilities Clinic/CenterAug 29, 2016
133669543629 N ACADEMY ST, GreenvilleDevelopmental Disabilities Clinic/CenterAug 29, 2016
167902977165 INTERNATIONAL DR, GreenvilleGeneral Acute Care HospitalAug 29, 2016
1174079271877 W FARIS RD, GreenvilleGeneral Acute Care HospitalAug 29, 2016
1871049973701 GROVE RD, GreenvilleSpecial HospitalAug 29, 2016
1538615653440 ROPER MOUNTAIN RD SUITE C, GreenvilleHome Health AgencyAug 29, 2016
1649726738701 GROVE RD, GreenvilleGeneral Acute Care HospitalAug 29, 2016
1285180307875 W FARIS RD, GreenvilleMulti-Specialty Clinic/CenterAug 29, 2016
15083126049 DOCTORS DR, GreenvilleGeneral Acute Care HospitalAug 29, 2016
181143964929 N ACADEMY ST, GreenvilleMedically Fragile Infants and Children Day CareNov 10, 2016
179026449711404 ANDERSON RD, GreenvilleGeneral Acute Care HospitalAug 13, 2018
157804405311402 ANDERSON RD STE B, GreenvilleGeneral Acute Care HospitalAug 23, 2018
1396207221905 VERDAE BLVD STE 102, GreenvilleGeneral Acute Care HospitalApr 1, 2019
1730770744207 THREE BRIDGES RD, GreenvilleRural Health Clinic/CenterFeb 2, 2021
197218609615 ROE RD, GreenvilleRural Health Clinic/CenterMay 5, 2021
1770167728209 THREE BRIDGES RD, GreenvilleRural Health Clinic/CenterMay 6, 2021
1720747496890 W FARIS RD STE 510, GreenvilleGeneral Acute Care HospitalDec 10, 2021
1730804246200 PATEWOOD DR STE B100, GreenvilleGeneral Acute Care HospitalOct 6, 2022
1144914607200 PATEWOOD DR STE C320, GreenvilleGeneral Acute Care HospitalJun 7, 2023
1376223180207 THREE BRIDGES RD, GreenvilleMulti-Specialty Clinic/CenterJul 18, 2023
1922788728905 VERDAE BLVD STE 102, GreenvilleGeneral Acute Care HospitalJul 18, 2023
1285314096209 THREE BRIDGES RD, GreenvilleMulti-Specialty Clinic/CenterJul 18, 2023
126511207215 ROE RD, GreenvilleMulti-Specialty Clinic/CenterJul 18, 2023
1649033077890 W FARIS RD STE 100, GreenvilleGeneral Acute Care HospitalJan 30, 2024
1952163339155B HALTON VILLAGE CIR, GreenvilleGeneral Acute Care HospitalJan 30, 2024
165913407010 HALTON GREEN WAY, GreenvilleGeneral Acute Care HospitalJan 31, 2024
1861235426157 WELBORN ST UNIT B101, GreenvilleGeneral Acute Care HospitalJun 13, 2024
132688498264 CENTENNIAL WAY, GreenvilleGeneral Acute Care HospitalJul 3, 2024
1841746948340 MEDICAL PKWY, GreerGeneral Acute Care HospitalAug 29, 2016
1982150009830 S BUNCOMBE RD, GreerGeneral Acute Care HospitalAug 29, 2016
1538658455109 PHYSICIANS DRIVE SUITE A, GreerClinic/CenterMay 7, 2018
1821760430340 MEDICAL PKWY STE 250, GreerGeneral Acute Care HospitalOct 1, 2021
1942755848106 PARKVIEW DR, LaurensRural Health Clinic/CenterAug 20, 2016
1659051464106 PARKVIEW DR, LaurensMulti-Specialty Clinic/CenterJul 18, 2023
15882404931115 WREN SCHOOL RD, PiedmontRural Health Clinic/CenterMar 22, 2021
1295188704300 MEMORIAL DR, SenecaLand AmbulanceJul 20, 2016
1720533474101 LILA DOYLE DR, SenecaSkilled Nursing FacilityAug 23, 2016
1437605524109 OMNI DR SUITE B, SenecaRural Health Clinic/CenterAug 29, 2016
1063968196298 MEMORIAL DR, SenecaGeneral Acute Care HospitalAug 29, 2016
1821544925131 LILA DOYLE DR, SenecaGeneral Acute Care HospitalAug 29, 2016
1134675242390 KEOWEE SCHOOL RD, SenecaInpatient HospiceAug 29, 2016
1891237632102B OMNI DR, SenecaPain Clinic/CenterNov 10, 2016
1407345846139 LILA DOYLE DRIVE, SenecaClinic/CenterMay 1, 2018
193274681510110 CLEMSON BLVD, SenecaRural Health Clinic/CenterDec 10, 2019
117416180611082 N RADIO STATION RD, SenecaRural Health Clinic/CenterDec 12, 2019
170042443912016 N RADIO STATION RD, SenecaRural Health Clinic/CenterDec 12, 2019
1154914158103 CARTER PARK DR STE A, SenecaRural Health Clinic/CenterFeb 19, 2021
1215617097109 OMNI DR STE B, SenecaMulti-Specialty Clinic/CenterJul 18, 2023
156814237010110 CLEMSON BLVD, SenecaMulti-Specialty Clinic/CenterJul 18, 2023
1699455493103 CARTER PARK DR STE A, SenecaMulti-Specialty Clinic/CenterJul 18, 2023
164995045211082 N RADIO STATION RD, SenecaMulti-Specialty Clinic/CenterJul 18, 2023
169945540212016 N RADIO STATION RD, SenecaMulti-Specialty Clinic/CenterJul 18, 2023
1982159877741 SE MAIN ST, SimpsonvilleSleep Disorder Diagnostic Clinic/CenterAug 20, 2016
1447706569729 SE MAIN ST, SimpsonvilleGeneral Acute Care HospitalAug 29, 2016
1265988364719A SE MAIN ST, SimpsonvilleGeneral Acute Care HospitalAug 29, 2016
1417505694729 SE MAIN ST, SimpsonvilleGeneral Acute Care HospitalAug 30, 2019
1003626326727 SE MAIN ST STE 180, SimpsonvilleGeneral Acute Care HospitalJan 9, 2025
16294328691413 JOHN B WHITE SR BLVD STE D, SpartanburgGeneral Acute Care HospitalApr 13, 2016
1427504554807 N MAIN ST, Travelers RestLong Term Care HospitalAug 29, 2016
1205459443807 N MAIN ST, Travelers RestRural Health Clinic/CenterMay 22, 2020
1609556489807 N MAIN ST, Travelers RestMulti-Specialty Clinic/CenterJul 18, 2023
1043857998103 WHITETAIL DR, WalhallaRural Health Clinic/CenterDec 10, 2019
1689353906103 WHITETAIL DR, WalhallaMulti-Specialty Clinic/CenterJul 13, 2023

Related names

  1. Prisma Health-Upstate DBA Ph North Greenville Er1 NPI

Checking an organization

  1. Match the NPI to the exact location you will visit or bill; each location can have its own.
  2. Confirm the business entity with the secretary of state.
  3. Check the HHS-OIG exclusion list for the organization and its owners.
  4. Verify each clinician you will see on their own record and with the state license search.

Common questions

Why does Prisma Health Upstate have 105 NPIs?

An organization may obtain more than one Type 2 NPI, for example for separate locations or units that bill on their own. Prisma Health Upstate's NPIs list practice locations in 16 cities.

Is an organization NPI a license?

No. An NPI identifies who bills. Facilities and the clinicians who work there are licensed separately by the state.

Source: CMS National Plan and Provider Enumeration System (NPPES), monthly file of Aug 9, 2026 (NPPES files on CMS.gov). An NPI identifies who bills; it is not a license.