Cassandra S. Destefano, PA-C
Physician Assistant · Harrisburg, PA
Cassandra S. Destefano, PA-C is a physician assistant with a practice address in Harrisburg, Pennsylvania, and NPI 1326455791, issued on Jul 17, 2014. Check the license (Pennsylvania MA056943, as entered in NPPES) with the Pennsylvania board that licenses this profession; the Medicare figures below come from public CMS files.
- Name
- Cassandra S. Destefano
- Credential
- PA-C
- Primary taxonomy
- Physician Assistant 363A00000X
- License number
- MA056943 PA
Self-reported in NPPES; status is on the state search - Practice location
- 2310 Patton RD, Harrisburg, PA 17112
- Phone
- (717) 724-6500
- Enumerated
- Jul 17, 2014
- Record last updated
- Mar 28, 2023
- Fax
- (717) 724-6510
- Medicare enrollment
- Enrolled (PECOS I20141009000299); may accept Medicare assignment
- Telehealth
- Offers telehealth (CMS)
- Entity
- Type 1 · individual
8 nearest physician assistant records → All 8,020 in Pennsylvania → Look up another NPI →
Also registered at 2310 Patton RD
A shared address usually means a shared clinic or building; it does not show who employs whom.
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- Jane Conroy, D.O.Family Medicine Physician1679542997
- John Dea, MDFamily Medicine Physician1992763726
- Patricia Himes, CRNPFamily Nurse Practitioner1578572715
- Lauren Hunsberger, CRNPFamily Nurse Practitioner1801485966
Verify Cassandra S. Destefano in five checks
- 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
- 2LicenseActive license and public ordersWhich Pennsylvania board licenses this profession
Search for license MA056943Check the board - 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
- 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
- 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
8.4 times the Medicare Part D claims of the average physician assistant in 2024
7,000 Medicare Part D claims for 1,047 beneficiaries, against an average of 830 among the 101,058 providers of this specialty who prescribed in Part D. Brand-name drugs were 8% of claims. 83 claims were for opioids.
Most prescribed
- Atorvastatin Calcium519 claims
- Amlodipine Besylate327 claims
- Lisinopril230 claims
- Levothyroxine Sodium229 claims
- Losartan Potassium210 claims
- Pantoprazole Sodium158 claims
Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.
The practice group's MIPS final score for 2023 (Medicare payment program): 82.5 of 100
The Merit-based Incentive Payment System score is reported for the practice group, not for one clinician alone. Four categories are weighted into the final score; the average among 454,083 clinicians with a measured score was 83.5.
Source: CMS Quality Payment Program, MIPS performance year 2023, group reporting; category weights for 2023 (qpp.cms.gov).
Bills Medicare through 2 group practices
- Pinnacle Health Medical ServicesHarrisburg, PA
- Pshr Physical Therapy, LLCHershey, PA
Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).
Cassandra S. Destefano among 8,020 physician assistant records in Pennsylvania
Cassandra S. Destefano, PA-C is one of 8,020 physician assistant records with a practice address in Pennsylvania. 80% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2014, is newer than 38% of them.
- NPI issued2014 · 38% of these records are older, 59% newer
- In a Medicare fileYes · 80% of these records are
- In the CMS Doctors and Clinicians fileYes · 66% of these records are
- Graduated2014 · median 2018 among the 5,313 with a school on file
- Record last updated2023 · 42% of these records were not updated in five years or more
Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 363A00000X and a Pennsylvania practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).
147 physician assistant records list a practice address in Harrisburg
They are 147 of the 3,963 NPPES records with a practice address in Harrisburg, and 8,020 physician assistant records in Pennsylvania.
All 8,020 in Pennsylvania → Every provider in Harrisburg → Physician Assistant nationwide →
The 8 physician assistant records with the nearest ZIP codes
- Jamie Cantafio, PA-CHarrisburg, PA 171121750641825
- Jessica Chaudry, PA-CHarrisburg, PA 171121346670478
- John Conway, PA-CHarrisburg, PA 171121275185167
- Ruchi Dalal, PA-CHarrisburg, PA 171121407311525
- Patricia Freudenberger, PA-CHarrisburg, PA 171121366932485
- Rachel Hikes, PA-CHarrisburg, PA 171121821402454
- Pamela Hoenich, PA-CHarrisburg, PA 171121437524287
- Jennifer Kmiecinski, PA-CHarrisburg, PA 171121508005661
Common questions
What is Cassandra S. Destefano, PA-C's NPI number?
Cassandra S. Destefano, PA-C's National Provider Identifier (NPI) is 1326455791, issued on Jul 17, 2014. An NPI identifies a provider in billing; it is not a license.
Where is Cassandra S. Destefano, PA-C located?
The NPPES record lists a practice address at 2310 Patton RD, Harrisburg, PA, 17112. Phone: (717) 724-6500. Providers update this record themselves, so call before visiting.
How can I verify Cassandra S. Destefano, PA-C's license?
NPPES lists Pennsylvania license number MA056943, as entered by the provider. Search the Pennsylvania board that licenses this profession; the NPPES record confirms identity only.
How much does Cassandra S. Destefano, PA-C prescribe under Medicare Part D?
In 2024, Cassandra S. Destefano, PA-C had 7,000 Medicare Part D claims for 1,047 beneficiaries; the average among physician assistant prescribers was 830. Part D covers Medicare prescriptions only.
What is Cassandra S. Destefano, PA-C's MIPS final score?
The 2023 MIPS final score is 82.5 of 100, reported for the practice group. The average among 454,083 clinicians with a measured score was 83.5.
Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.
Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.