Darryl B. Best, M.D.
Internal Medicine Physician · Greenwood, SC
Darryl B. Best, M.D. is an internal medicine physician with a practice address in Greenwood, South Carolina, and NPI 1215973219, issued on Jun 20, 2006. Check the license (South Carolina 18134, as entered in NPPES) on the South Carolina Board of Medical Examiners; the Medicare figures below come from public CMS files.
- Name
- Darryl B. Best
- Credential
- M.D.
- Primary taxonomy
- Internal Medicine Physician 207R00000X
- License number
- 18134 SC
Self-reported in NPPES; status is on the state search - Practice location
- 1325 Spring St, Greenwood, SC 29646
- Phone
- (864) 725-4272
- Enumerated
- Jun 20, 2006
- Record last updated
- Mar 26, 2015 (not updated in 11 years: call before relying on the address or phone)
- Fax
- (864) 725-4452
- Medicaid ID
- 181341 SC
- Medicare enrollment
- Enrolled (PECOS I20040806001028); accepts Medicare assignment
- Medical or professional school
- Medical University Of South Carolina College Of Medicine, 1989
- Telehealth
- Offers telehealth (CMS)
- Entity
- Type 1 · individual
8 nearest internal medicine physician records → All 1,881 in South Carolina → Look up another NPI →
Also registered at 1325 Spring St
A shared address usually means a shared clinic or building; it does not show who employs whom.
- Tinu Abraham, MDInternal Medicine Physician1194354399
- Chandler Adams, PA-CPhysician Assistant1205465820
- Matthew Adams, MDFamily Medicine Physician1467136135
- Kelly Addy, NPFamily Nurse Practitioner1790215291
- Sunil Agarwal, MDPain Medicine (Anesthesiology) Physician1780113506
- Solomon Amemasor, DODiagnostic Radiology Physician1285128892
Verify Darryl B. Best in five checks
- 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
- 2LicenseActive license and public ordersSouth Carolina Board of Medical Examiners
Search for license 18134Check the board - 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
- 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
- 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
33% more Medicare Part D claims than the average internal medicine physician in 2024
4,212 Medicare Part D claims for 272 beneficiaries, against an average of 3,176 among the 108,855 providers of this specialty who prescribed in Part D. Brand-name drugs were 19% of claims.
Most prescribed
- Albuterol Sulfate Hfa216 claims
- Atorvastatin Calcium211 claims
- Amlodipine Besylate146 claims
- Montelukast Sodium139 claims
- Gabapentin128 claims
- Fluticasone Propionate127 claims
Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.
Industry payments in 2024: $773.18
26 payments; by number, the most common kind was food and beverage; the largest payer was AstraZeneca Pharmaceuticals LP. The 50,334 providers of this specialty with any payment received $1,303.06 on average. Payments are reported by manufacturers, not by the provider, and are not a sign of wrongdoing.
Source: CMS Open Payments, program year 2024 (openpaymentsdata.cms.gov); average among providers of this specialty with at least one payment.
Bills Medicare through one group practice
- Pecora Medical, PCAnderson, SC
Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).
Darryl B. Best among 1,881 internal medicine physician records in South Carolina
Darryl B. Best, M.D. is one of 1,881 internal medicine physician records with a practice address in South Carolina. 81% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2006, is newer than 7% of them.
- NPI issued2006 · 7% of these records are older, 58% newer
- In a Medicare fileYes · 81% of these records are
- In the CMS Doctors and Clinicians fileYes · 60% of these records are
- Graduated1989 · median 2006 among the 1,119 with a school on file
- Record last updated2015 · 46% of these records were not updated in five years or more
Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 207R00000X and a South Carolina practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).
23 internal medicine physician records list a practice address in Greenwood
They are 23 of the 1,262 NPPES records with a practice address in Greenwood, and 1,881 internal medicine physician records in South Carolina.
All 1,881 in South Carolina → Every provider in Greenwood → Internal Medicine Physician nationwide →
The 8 internal medicine physician records with the nearest ZIP codes
- Samuel Burnett III, M.D.Greenwood, SC 296461942296074
- Orr Cobb, M.D.Greenwood, SC 296461952397085
- George Cone, MDGreenwood, SC 296461689666703
- Brian Gunter, MDGreenwood, SC 296461255497640
- Russell Hall, M.D.Greenwood, SC 296461265429492
- John Holman, M.D.Greenwood, SC 296461922095405
- Carlos Manalich, M.D.Greenwood, SC 296461003871997
- Lincoln McGinnis, MDGreenwood, SC 296461205822319
Common questions
What is Darryl B. Best, M.D.'s NPI number?
Darryl B. Best, M.D.'s National Provider Identifier (NPI) is 1215973219, issued on Jun 20, 2006. An NPI identifies a provider in billing; it is not a license.
Where is Darryl B. Best, M.D. located?
The NPPES record lists a practice address at 1325 Spring St, Greenwood, SC, 29646. Phone: (864) 725-4272. Providers update this record themselves, so call before visiting.
How can I verify Darryl B. Best, M.D.'s license?
NPPES lists South Carolina license number 18134, as entered by the provider. Search the South Carolina Board of Medical Examiners at https://verify.llronline.com/LicLookup/Med/Med.aspx?div=22. The NPPES record confirms identity only; the state search shows license status, expiration and public orders.
How much does Darryl B. Best, M.D. prescribe under Medicare Part D?
In 2024, Darryl B. Best, M.D. had 4,212 Medicare Part D claims for 272 beneficiaries; the average among internal medicine physician prescribers was 3,176. Part D covers Medicare prescriptions only.
Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.
Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.