NPPES file of Aug 9, 2026

Guadalupe Santiago Santiago

Internal Medicine Physician · Arecibo, PR

Guadalupe Santiago Santiago is an internal medicine physician with a practice address in Arecibo, Puerto Rico, and NPI 1558322826, issued on Mar 28, 2006. Check the license (Puerto Rico 207R00000X, as entered in NPPES) with the Puerto Rico board that licenses this profession; the Medicare figures below come from public CMS files.

Record from CMS NPPES, file of Aug 9, 2026 · Medicare files 2024 · method · Verify with CMS →

NPPES recordNPPES file of Aug 9, 2026
1558322826
Name
Guadalupe Santiago Santiago
Primary taxonomy
Internal Medicine Physician 207R00000X
License number
207R00000X PR
Self-reported in NPPES; status is on the state search
Practice location
Num 50 Ave Trina Padilla DE Sanz, Arecibo, PR 00612
Phone
(787) 879-3978
Enumerated
Mar 28, 2006
Record last updated
Jan 28, 2013 (not updated in 13 years: call before relying on the address or phone)
Fax
(787) 880-3789
Medicare enrollment
Enrolled (PECOS I20061206000330); accepts Medicare assignment
Medical or professional school
University Central Del Caribe Escuela De Medicina, 1981
Entity
Type 1 · individual
Public record from CMS NPPES (open it on the CMS NPI Registry). Enrollment, assignment, school and telehealth: CMS Doctors and Clinicians file, Aug 2026. A record is not a license: verify it with the state board.
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Verify Guadalupe Santiago Santiago in five checks

  1. 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
  2. 2LicenseActive license and public ordersWhich Puerto Rico board licenses this profession
    Search for license 207R00000X
    Check the board
  3. 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
  4. 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
  5. 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
Find the Puerto Rico license search

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73% more Medicare Part D claims than the average internal medicine physician in 2024

5,499 Medicare Part D claims for 422 beneficiaries, against an average of 3,176 among the 108,855 providers of this specialty who prescribed in Part D. Brand-name drugs were 13% of claims. 11 claims were for opioids.

  1. Guadalupe Santiago5,499
  2. Specialty average3,176

Most prescribed

  1. Gabapentin359 claims
  2. Losartan Potassium212 claims
  3. Famotidine202 claims
  4. Amlodipine Besylate186 claims
  5. Simvastatin159 claims
  6. Synthroid159 claims

Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.

Industry payments in 2024: $361.95

3 payments; by number, the most common kind was food and beverage; the largest payer was AstraZeneca Pharmaceuticals LP. The 50,334 providers of this specialty with any payment received $1,303.06 on average. Payments are reported by manufacturers, not by the provider, and are not a sign of wrongdoing.

  1. Guadalupe Santiago$361.95
  2. Specialty average$1,303.06

Source: CMS Open Payments, program year 2024 (openpaymentsdata.cms.gov); average among providers of this specialty with at least one payment.

Guadalupe Santiago Santiago among 1,146 internal medicine physician records in Puerto Rico

Guadalupe Santiago Santiago is one of 1,146 internal medicine physician records with a practice address in Puerto Rico. 79% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2006, is newer than 13% of them.

  • NPI issued2006 · 13% of these records are older, 52% newer
  • In a Medicare fileYes · 79% of these records are
  • In the CMS Doctors and Clinicians fileYes · 52% of these records are
  • Graduated1981 · median 1996 among the 595 with a school on file
  • Record last updated2013 · 55% of these records were not updated in five years or more

Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 207R00000X and a Puerto Rico practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).

22 internal medicine physician records list a practice address in Arecibo

They are 22 of the 976 NPPES records with a practice address in Arecibo, and 1,146 internal medicine physician records in Puerto Rico.

The 8 internal medicine physician records with the nearest ZIP codes

  1. Felix Colon, M.D.Arecibo, PR 006121821069337
  2. Mirtha Miraglia, MDArecibo, PR 006121386475176
  3. Jose Ortega Velez, M.D.Arecibo, PR 006121134209935
  4. Victor Perez-Gonzalez, MDArecibo, PR 006121104356468
  5. Francis Picon, MDArecibo, PR 006121639289317
  6. Manuel Polanco Martinez, MDArecibo, PR 006121184664757
  7. Raul Rivera, M.D.Arecibo, PR 006121679672356
  8. Abel Rivera RomanArecibo, PR 006121841180015

Common questions

What is Guadalupe Santiago Santiago's NPI number?

Guadalupe Santiago Santiago's National Provider Identifier (NPI) is 1558322826, issued on Mar 28, 2006. An NPI identifies a provider in billing; it is not a license.

Where is Guadalupe Santiago Santiago located?

The NPPES record lists a practice address at Num 50 Ave Trina Padilla DE Sanz, Arecibo, PR, 00612. Phone: (787) 879-3978. Providers update this record themselves, so call before visiting.

How can I verify Guadalupe Santiago Santiago's license?

NPPES lists Puerto Rico license number 207R00000X, as entered by the provider. Search the Puerto Rico board that licenses this profession; the NPPES record confirms identity only.

How much does Guadalupe Santiago Santiago prescribe under Medicare Part D?

In 2024, Guadalupe Santiago Santiago had 5,499 Medicare Part D claims for 422 beneficiaries; the average among internal medicine physician prescribers was 3,176. Part D covers Medicare prescriptions only.

Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.

Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.