Isaac Edward Alwine, M.D.
Hematology & Oncology Physician · Spartanburg, SC
Isaac Edward Alwine, M.D. is a hematology & oncology physician with a practice address in Spartanburg, South Carolina, and NPI 1619364668, issued on Apr 16, 2015. Check the license (South Carolina 38531, as entered in NPPES) on the South Carolina Board of Medical Examiners; the Medicare figures below come from public CMS files.
- Name
- Isaac Edward Alwine
- Credential
- M.D.
- Primary taxonomy
- Hematology & Oncology Physician 207RH0003X
- License number
- 38531 SC
Self-reported in NPPES; status is on the state search - Practice location
- 101 E Wood St, Spartanburg, SC 29303
- Phone
- (864) 560-7050
- Enumerated
- Apr 16, 2015
- Record last updated
- Aug 4, 2021 (not updated in 5 years: call before relying on the address or phone)
- Fax
- (864) 560-0800
- Medicaid ID
- 385318 SC
- Medicare enrollment
- Enrolled (PECOS I20210723002609); accepts Medicare assignment
- Entity
- Type 1 · individual
Also registered at 101 E Wood St
A shared address usually means a shared clinic or building; it does not show who employs whom.
- Michelle Abel, PNP-PCNurse Practitioner1639977762
- Dustin Abele, M.D.Family Medicine Physician1851771349
- Elizabeth Abell, MDInfectious Disease Physician1083623805
- Martine Abouchabki, PHARMDPharmacist1952299356
- Samuel Adams, MDInternal Medicine Physician1568026607
- Samuel Adediran, M.D.,Hematology & Oncology Physician1811259096
Verify Isaac Edward Alwine in five checks
- 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
- 2LicenseActive license and public ordersSouth Carolina Board of Medical Examiners
Search for license 38531Check the board - 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
- 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
- 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
3.1 times the Medicare Part D claims of the average hematology & oncology physician in 2024
2,757 Medicare Part D claims for 467 beneficiaries, against an average of 877 among the 10,784 providers of this specialty who prescribed in Part D. Brand-name drugs were 8% of claims. 134 claims were for opioids.
Most prescribed
- Letrozole977 claims
- Ibandronate Sodium355 claims
- Anastrozole122 claims
- Ondansetron Odt74 claims
- Ondansetron Hcl60 claims
- Prochlorperazine Maleate60 claims
Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.
The MIPS final score for 2023 (Medicare payment program): 96.1 of 100
The Merit-based Incentive Payment System score is reported for this clinician. Four categories are weighted into the final score; the average among 454,083 clinicians with a measured score was 83.5.
Source: CMS Quality Payment Program, MIPS performance year 2023; category weights for 2023 (qpp.cms.gov).
Industry payments in 2024: $619.27
26 payments; by number, the most common kind was food and beverage; the largest payer was Abbvie Inc. The 8,560 providers of this specialty with any payment received $7,481.41 on average. Payments are reported by manufacturers, not by the provider, and are not a sign of wrongdoing.
Source: CMS Open Payments, program year 2024 (openpaymentsdata.cms.gov); average among providers of this specialty with at least one payment.
One hospital affiliation
- Spartanburg Medical CenterSpartanburg, SC · Acute Care Hospitals2 of 5 stars
Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through); hospitals matched to CMS Hospital General Information (Care Compare) (data.cms.gov). Star ratings are CMS hospital ratings, not ratings of this provider.
Hematology & Oncology Physician providers in South Carolina
There are 181 hematology & oncology physician records in South Carolina.
Other hematology & oncology physician records in South Carolina
- Mary Ackerman, MDColumbia, SC1912988536
- Sara Adams, M.D.Georgetown, SC1043397391
- Samuel Adediran, M.D.,Spartanburg, SC1811259096
- Priyal Agarwal, MDCharleston, SC1386206340
- Reem Akel, MDFlorence, SC1619461852
- Steven Akman, MDCharleston, SC1396729414
- Jonathan Alexander, M.D.Charleston, SC1619409257
- Faria Ali, MDMyrtle Beach, SC1225565666
- Katherine Antel, MD, PHDCharleston, SC1518799022
- William Babcock, MDColumbia, SC1538140173
Common questions
What is Isaac Edward Alwine, M.D.'s NPI number?
Isaac Edward Alwine, M.D.'s National Provider Identifier (NPI) is 1619364668, issued on Apr 16, 2015. An NPI identifies a provider in billing; it is not a license.
Where is Isaac Edward Alwine, M.D. located?
The NPPES record lists a practice address at 101 E Wood St, Spartanburg, SC, 29303. Phone: (864) 560-7050. Providers update this record themselves, so call before visiting.
How can I verify Isaac Edward Alwine, M.D.'s license?
NPPES lists South Carolina license number 38531, as entered by the provider. Search the South Carolina Board of Medical Examiners at https://verify.llronline.com/LicLookup/Med/Med.aspx?div=22. The NPPES record confirms identity only; the state search shows license status, expiration and public orders.
How much does Isaac Edward Alwine, M.D. prescribe under Medicare Part D?
In 2024, Isaac Edward Alwine, M.D. had 2,757 Medicare Part D claims for 467 beneficiaries; the average among hematology & oncology physician prescribers was 877. Part D covers Medicare prescriptions only.
What is Isaac Edward Alwine, M.D.'s MIPS final score?
The 2023 MIPS final score is 96.1 of 100. The average among 454,083 clinicians with a measured score was 83.5.
Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.
Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.