NPI registry status
Active
2026 NPPES data Hematology (Internal Medicine) Physician NPI 1477643955 MD
Verify on CMS → Issam Makhoul, MD
Hematology (Internal Medicine) Physician in Little Rock, Arkansas.
This profile is drawn from the federal National Provider Identifier Registry (CMS NPPES), which lists more than 7 million U.S. healthcare providers - including 1,436 in Hematology (Internal Medicine) Physician, and covers specialty classification, practice address, and Medicare Part D prescribing data when reported. According to CMS, every field reflects the provider's official federal registration, see our methodology.
Federal data, no proprietary rating.
We show these CMS records as-is - no composite score, no star rating, no editorial opinion layered on top.
Prescribing volume
1K
Medicare Part D claims · 107 beneficiaries · Hematology (Internal Medicine) Physician avg: 693
Industry payments
$75.86
3 payments · CMS Open Payments (Sunshine Act)
Compiled from official public sources by the PlainDoctor editorial team.
What the federal data shows
Issam Makhoul, MD filed 1,095 Medicare Part D claims in 2023 as a Hematology (Internal Medicine) Physician in Little Rock, Arkansas.
- 1K
- Part D claims, 2023
- Likely
- board-certified (heuristic)
Every figure on this page comes straight from federal CMS records (NPPES, Medicare Part D, MIPS, Open Payments) - no proprietary rating or editorial opinion is applied.
Issam Makhoul, MD's Medicare Part D volume vs every U.S. prescriber
Total Medicare Part D claims, 2023, across all CMS prescribers nationally
1,095 Top 24% higher than 76% of 1,370,886 prescribers
Each bar is a band; taller bars hold more prescribers. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.
Source CMS Medicare Part D Prescriber Public Use File · 2023
✓
Board certification likely (heuristic, not verified)
Issam Makhoul, MD practices in an ABMS-board-eligible specialty and shows active CMS Medicare participation + 1 hospital affiliation - signals consistent with board-certified status. For verified board certification, see CertificationMatters.org (the official ABMS public lookup).
What does the federal data show about Issam Makhoul, MD?
Quality data not reportedPrimary specialty
Hematology (Internal Medicine) Physician
Medicare Part D claims
1,095 58% vs specialty avg
Specialty distribution in Arkansas
How Hematology (Internal Medicine) Physician compares to other specialties among Arkansas providers
Board certification
Not published by CMS
CMS does not publish a per-provider board-certification field in NPPES. PlainDoctor does not have a reliable per-specialty certification rate to show for Hematology (Internal Medicine) Physician. Verify directly:
How MIPS and board certification work
The Merit-based Incentive Payment System (MIPS) scores providers 0–100 across four performance categories: Quality, Cost, Promoting Interoperability, and Improvement Activities, weighted under 42 CFR §414.1380. Reporting is voluntary for many small practices, so absence of a MIPS score is not a quality signal.
Board certification through an ABMS or AOA member board signals voluntary post-licensure examination plus continuous Maintenance of Certification cycles. Verify any individual provider's status through certificationmatters.org (ABMS) or osteopathic.org (AOA).
Issam Makhoul, MD appears in the CMS NPPES registry as a Hematology (Internal Medicine) Physician provider holding MD credentials at 8901 CARTI WAY, Little Rock, AR, 72205, with a listed phone of (015) 906-3000. NPI 1477643955 was issued on 10/13/2006.
Medicare Part D records for calendar year 2023 show 1,095 prescription claims written by this provider, covering 107 Medicare beneficiaries and totaling roughly $1.6 million in drug spend, with an opioid prescribing rate of 7.4%.
Hematology (Internal Medicine) Physician is a narrow specialty nationwide, with 1,436 enrolled providers across 50 states and an average of 693 Part D claims per prescriber, so the context for interpreting these metrics differs meaningfully from a primary-care baseline.
Important: PlainDoctor is a directory of publicly available government data, not medical advice, a malpractice database, or a quality rating. Inclusion here does not imply a recommendation, and absence of complaints or sanctions on this page does not mean none exist, always verify credentials through the NPPES NPI Registry, your state medical board, and the ABMS or AOA before making healthcare decisions.
Practice Address
Provider Details
| NPI | 1477643955 |
|---|---|
| Specialty | Hematology (Internal Medicine) Physician |
| Credentials | MD |
| Gender | Male |
| NPI Issued | 10/13/2006 |
Hospital and facility affiliations
Facilities where Issam Makhoul, MD bills Medicare from. Star ratings (1-5) are CMS Hospital Compare's "Hospital overall rating" - a composite of mortality, readmission, patient experience, safety, timely care, and efficient use of medical imaging measures. Source: CMS Care Compare.
Central Arkansas Radiation Therapy Institute Inc
Little Rock, AR
Affiliations sourced from CMS Doctors and Clinicians National Downloadable File; hospital ratings from CMS Hospital General Information dataset (cross-referenced by facility name + state).
Industry payments received (2024) - CMS Open Payments transparency data
The federal Physician Payments Sunshine Act (part of the Affordable Care Act) requires drug and medical-device manufacturers + group purchasing organizations to publicly report payments and other transfers of value to physicians and teaching hospitals. The data below covers 2024 for Issam Makhoul, MD. Source: openpaymentsdata.cms.gov.
Total received
$76
Largest payer
Merck Sharp & Dohme LLC
Most common payment type
Food and Beverage
Industry payments are not necessarily indicators of bias, they include research funding, consulting fees for evidence-based work, royalties for inventions, food at conferences, and similar items. The disclosure exists for transparency. Read our methodology for how we interpret this data.
Medicare Part D Prescribing Data
CMS Medicare Part D prescriber-level data for calendar year 2023.
1,095
Total Claims
$1.6M
Total Drug Cost
107
Medicare Beneficiaries
Prescribing Breakdown
- 30-Day Fills
- 1,366
- Total Day Supply
- 36,806
- Generic Drug Cost
- $134K
- Opioid Claims
- 81 (7.4% rate)
- Antibiotic Claims
- 31
Patient Demographics
- Average Patient Age
- 71.1 years
- Avg HCC Risk Score
- 1.99
- Gender Split
- 84% female / 16% male
Top Prescribed Drugs (Medicare Part D)
Top drugs by claim count for calendar year 2023. Based on Medicare Part D data only.
What Issam Makhoul, MD prescribes most
Top Medicare Part D drugs by claim count, 2023
- Anastrozole
Anastrozole
114 claims
- Letrozole
Letrozole
64 claims
- Gabapentin
Gabapentin
58 claims
- Levothyroxine Sodium
Levothyroxine Sodium
47 claims
- Fulvestrant 33
Fulvestrant
33 claims
- Creon 31
Creon
31 claims
- Neulasta Onpro 30
Neulasta Onpro
30 claims
- Prednisone 29
Prednisone
29 claims
| Drug | Claims |
|---|---|
| Anastrozole | 114 |
| Letrozole | 64 |
| Gabapentin | 58 |
| Levothyroxine Sodium | 47 |
| Fulvestrant | 33 |
| Creon Lipase/Protease/Amylase | 31 |
| Neulasta Onpro Pegfilgrastim | 30 |
| Prednisone | 29 |
| Hydrocortisone | 28 |
| Prochlorperazine Maleate | 24 |
* Counts below 11 are suppressed by CMS for patient privacy. Generic names shown where available from CMS Part D data.
More Hematology (Internal Medicine) Physician in AR →
All providers in Arkansas →
Compare specialties →
Hematology (Internal Medicine) Physician Overview
How Issam Makhoul, MD fits within the Hematology (Internal Medicine) Physician landscape nationally.
1,436
Hematology (Internal Medicine) Physician Providers in US
50
States with Hematology (Internal Medicine) Physician
693
Avg Claims per Provider
Issam Makhoul, MD's 1,095 claims are above the specialty average of 693.
Nearby Hematology (Internal Medicine) Physician Providers in Arkansas
Other clinicians with the same primary specialty enrolled in Arkansas, drawn from the same CMS NPPES roster as Makhoul.
Dr. Rebecca Fleck
MD
Fort Smith, AR
Dr. Michele Fox
MD
Little Rock, AR
Anusha Jillella
North Little Rock, AR
Dr. Atif Khan
MD
Batesville, AR
Compare Hematology (Internal Medicine) Physician nationally: see state-by-state distribution →
Before you book an appointment
Use this federal record as your verification checklist, not as a recommendation.
- Confirm the NPI record is current in the official CMS registry, providers update their own NPPES details, and moves can lag. Verify this NPI
- Check the active license and any disciplinary history with the Arkansas medical board, federal registration is not a license check. Credential verification guide
- Weigh a second option: compare this provider with a nearby Hematology (Internal Medicine) Physician peer on Medicare volume and prescribing patterns. Compare providers
Medicare Part D and MIPS figures describe practice patterns in federal programs only, they are not quality ratings, and PlainDoctor does not rate, rank, or recommend providers.
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Medical Specialties Explained
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Explore Arkansas
Frequently Asked Questions
What is Issam Makhoul, MD's specialty? ▼
Issam Makhoul, MD specializes in Hematology (Internal Medicine) Physician and practices in Little Rock, Arkansas. Credentials: MD.
How much does Issam Makhoul, MD prescribe under Medicare Part D? ▼
In 2023, Issam Makhoul, MD wrote 1,095 Medicare Part D claims totaling $1.6M in drug costs for 107 beneficiaries.
Where is Issam Makhoul, MD located? ▼
Issam Makhoul, MD is located at 8901 CARTI WAY, Little Rock, AR, 72205. Phone: (015) 906-3000.
What is Issam Makhoul, MD's NPI number? ▼
Issam Makhoul, MD's National Provider Identifier (NPI) is 1477643955, issued on 10/13/2006.
Does Issam Makhoul, MD prescribe opioids? ▼
Yes, Issam Makhoul, MD had 81 opioid claims in 2023 with an opioid prescribing rate of 7.4%.
How many Hematology (Internal Medicine) Physician providers are there in the US? ▼
There are 1,436 Hematology (Internal Medicine) Physician providers across 50 states in the US. The average Hematology (Internal Medicine) Physician provider writes 693 Medicare Part D claims per year.
What drugs does Issam Makhoul, MD prescribe most often? ▼
Based on 2023 Medicare Part D data, Issam Makhoul, MD's most frequently prescribed drugs include Anastrozole, Letrozole, Gabapentin. This reflects Medicare Part D prescriptions only and does not include commercial insurance or other payer types.
Does Issam Makhoul, MD accept Medicare? ▼
Issam Makhoul, MD appears in CMS Medicare data with 1,095 Part D claims and 107 Medicare beneficiaries in 2023. Contact the provider's office directly to confirm current Medicare enrollment and accepted plans.
How can I verify Issam Makhoul, MD's credentials? ▼
Issam Makhoul, MD's NPI is 1477643955 with credentials MD. You can verify this through the NPPES NPI Registry, check state medical board records, and confirm board certification through the ABMS or AOA.
Data Sources
View source datasets and methodology notes
- Provider Directory
- CMS National Plan and Provider Enumeration System (NPPES), download.cms.gov/nppes, updated monthly. Contains NPI, specialty, credentials, and practice location.
- Specialty Classification
- NUCC Health Care Provider Taxonomy (nucc.org), the industry standard for classifying provider specialties in Medicare and Medicaid billing.
- Prescribing Data
- CMS Medicare Part D Prescriber Public Use File (2023). Includes claims, drug costs, beneficiaries, and opioid prescribing rates.
- Limitations
- Provider data is self-reported to CMS. Prescribing data reflects Medicare Part D only and does not include commercial insurance, Medicaid, or cash prescriptions. Claims below 11 beneficiaries are suppressed by CMS for privacy.
See our complete data methodology for details on how we collect and process government data.
Data as of April 2026 (NPPES) / 2023 (Medicare Part D). Source: Centers for Medicare & Medicaid Services (CMS).
Disclaimer: Data from CMS NPPES and Medicare Part D. PlainDoctor does not rate or rank providers. Provider information is self-reported and may not be current. Always verify information directly with the provider. About · Methodology
Compiled from official public sources by the PlainDoctor editorial team.