NPPES file of Aug 9, 2026

Issam Makhoul, MD

Hematology & Oncology Physician · Little Rock, AR

Issam Makhoul, MD is a hematology & oncology physician with a practice address in Little Rock, Arkansas, and NPI 1477643955, issued on Oct 13, 2006. Check the license (Arkansas E-3306, as entered in NPPES) on the Arkansas State Medical Board; the Medicare figures below come from public CMS files.

Record from CMS NPPES, file of Aug 9, 2026 · Medicare files 2024 · method · Verify with CMS →

NPPES recordNPPES file of Aug 9, 2026
1477643955
Name
Issam Makhoul
Credential
MD
Primary taxonomy
Hematology & Oncology Physician 207RH0003X
License number
E-3306 AR
Self-reported in NPPES; status is on the state search
Practice location
8901 Carti Way, Little Rock, AR 72205
Phone
(015) 906-3000
Enumerated
Oct 13, 2006
Record last updated
Mar 9, 2022
Medicaid ID
148205001 AR
Medicare enrollment
Enrolled (PECOS I20100116000404); accepts Medicare assignment
Entity
Type 1 · individual
Public record from CMS NPPES (open it on the CMS NPI Registry). Enrollment, assignment, school and telehealth: CMS Doctors and Clinicians file, Aug 2026. A record is not a license: verify it with the state board.
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Also registered at 8901 Carti Way

A shared address usually means a shared clinic or building; it does not show who employs whom.

  1. Shakeylla Allen, APRNAcute Care Nurse Practitioner1538528765
  2. Juan Barreto Andrade, MDSurgical Oncology Physician1932350683
  3. Jillian Bell, OTD, OTR/LOccupational Therapist1255003067
  4. Cynara Bennett, APRN-BCGerontology Nurse Practitioner1144861709
  5. William Betzner, PHARMDPharmacist1376154468
  6. Jacob Brady, MDOtolaryngology Physician1659875425

Verify Issam Makhoul in five checks

  1. 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
  2. 2LicenseActive license and public ordersArkansas State Medical Board
    Search for license E-3306
    Check the board
  3. 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
  4. 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
  5. 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
Open the Arkansas license search

PlainDoctor does not match the HHS-OIG exclusion list to individual records: most entries carry no NPI. Search the OIG exclusion list by name.

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2.0 times the Medicare Part D claims of the average hematology & oncology physician in 2024

1,766 Medicare Part D claims for 147 beneficiaries, against an average of 877 among the 10,784 providers of this specialty who prescribed in Part D. 87 claims were for opioids.

  1. Issam Makhoul1,766
  2. Specialty average877

Most prescribed

  1. Anastrozole127 claims
  2. Gabapentin88 claims
  3. Letrozole86 claims
  4. Fulvestrant78 claims
  5. Neulasta Onpro60 claims
  6. Levothyroxine Sodium55 claims

Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.

Industry payments in 2024: $75.86

3 payments; by number, the most common kind was food and beverage; the largest payer was Merck Sharp & Dohme LLC. The 8,560 providers of this specialty with any payment received $7,481.41 on average. Payments are reported by manufacturers, not by the provider, and are not a sign of wrongdoing.

  1. Issam Makhoul$75.86
  2. Specialty average$7,481.41

Source: CMS Open Payments, program year 2024 (openpaymentsdata.cms.gov); average among providers of this specialty with at least one payment.

Bills Medicare through one group practice

  1. Central Arkansas Radiation Therapy Institute IncLittle Rock, AR

Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).

Issam Makhoul among 103 hematology & oncology physician records in Arkansas

Issam Makhoul, MD is one of 103 hematology & oncology physician records with a practice address in Arkansas. 90% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2006, is newer than 12% of them.

  • NPI issued2006 · 12% of these records are older, 51% newer
  • In a Medicare fileYes · 90% of these records are
  • In the CMS Doctors and Clinicians fileYes · 79% of these records are
  • Graduated1980 · median 2002 among the 80 with a school on file
  • Record last updated2022 · 34% of these records were not updated in five years or more

Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 207RH0003X and a Arkansas practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).

Hematology & Oncology Physician providers in Arkansas

There are 103 hematology & oncology physician records in Arkansas.

The 8 hematology & oncology physician records with the nearest ZIP codes

  1. Konstantinos Arnaoutakis, M.D.Little Rock, AR 722051053426304
  2. Joseph Beck, MDLittle Rock, AR 722051568441368
  3. Anthony Bucolo, M.D.Little Rock, AR 722051497752638
  4. Peter Emanuel, MDLittle Rock, AR 722051205844594
  5. Mariann Harrington, M.D.Little Rock, AR 722051184606071
  6. Kewen Jauss, M.D.Little Rock, AR 722051609984368
  7. Anuradha Kunthur, MDLittle Rock, AR 722051770526147
  8. Lawrence Mendelsohn, MDLittle Rock, AR 722051295717189

Common questions

What is Issam Makhoul, MD's NPI number?

Issam Makhoul, MD's National Provider Identifier (NPI) is 1477643955, issued on Oct 13, 2006. An NPI identifies a provider in billing; it is not a license.

Where is Issam Makhoul, MD located?

The NPPES record lists a practice address at 8901 Carti Way, Little Rock, AR, 72205. Phone: (015) 906-3000. Providers update this record themselves, so call before visiting.

How can I verify Issam Makhoul, MD's license?

NPPES lists Arkansas license number E-3306, as entered by the provider. Search the Arkansas State Medical Board at https://armedicalboard.adh.arkansas.gov/public/verify/. The NPPES record confirms identity only; the state search shows license status, expiration and public orders.

How much does Issam Makhoul, MD prescribe under Medicare Part D?

In 2024, Issam Makhoul, MD had 1,766 Medicare Part D claims for 147 beneficiaries; the average among hematology & oncology physician prescribers was 877. Part D covers Medicare prescriptions only.

Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.

Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.