NPPES file of Aug 9, 2026

James Matthew Brennan, M.D.

Internal Medicine Physician · Durham, NC

James Matthew Brennan, M.D. is an internal medicine physician with a practice address in Durham, North Carolina, and NPI 1164689105, issued on May 19, 2008. Check the license (North Carolina 135846, as entered in NPPES) on the North Carolina Medical Board; the Medicare figures below come from public CMS files.

Record from CMS NPPES, file of Aug 9, 2026 · Medicare files 2024 · method · Verify with CMS →

NPPES recordNPPES file of Aug 9, 2026
1164689105
Name
James Matthew Brennan
Credential
M.D.
Primary taxonomy
Internal Medicine Physician 207R00000X
License number
135846 NC
Self-reported in NPPES; status is on the state search
Practice location
1821 Hillandale RD Suite 25C, Durham, NC 27710
Phone
(919) 970-7773
Enumerated
May 19, 2008
Record last updated
Dec 30, 2021 (not updated in 5 years: call before relying on the address or phone)
Medicare enrollment
Enrolled (PECOS I20110908002359); accepts Medicare assignment
Medical or professional school
Univ Of Missouri-Kansas City School Of Dentistry, 2003
Entity
Type 1 · individual
Public record from CMS NPPES (open it on the CMS NPI Registry). Enrollment, assignment, school and telehealth: CMS Doctors and Clinicians file, Aug 2026. A record is not a license: verify it with the state board.
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Verify James Matthew Brennan in five checks

  1. 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
  2. 2LicenseActive license and public ordersNorth Carolina Medical Board
    Search for license 135846
    Check the board
  3. 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
  4. 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
  5. 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
Open the North Carolina license search

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2.5 times the Medicare Part D claims of the average internal medicine physician in 2024

7,956 Medicare Part D claims for 1,062 beneficiaries, against an average of 3,176 among the 108,855 providers of this specialty who prescribed in Part D. Brand-name drugs were 19% of claims.

  1. James Brennan7,956
  2. Specialty average3,176

Most prescribed

  1. Metoprolol Succinate823 claims
  2. Atorvastatin Calcium636 claims
  3. Eliquis583 claims
  4. Spironolactone518 claims
  5. Rosuvastatin Calcium501 claims
  6. Amlodipine Besylate468 claims

Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.

Industry payments in 2024: $96.16

3 payments; by number, the most common kind was food and beverage; the largest payer was Boston Scientific Corporation. The 50,334 providers of this specialty with any payment received $1,303.06 on average. Payments are reported by manufacturers, not by the provider, and are not a sign of wrongdoing.

  1. James Brennan$96.16
  2. Specialty average$1,303.06

Source: CMS Open Payments, program year 2024 (openpaymentsdata.cms.gov); average among providers of this specialty with at least one payment.

Bills Medicare through one group practice

  1. Duke Health Integrated Practice IncDurham, NC

Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).

James Matthew Brennan among 4,056 internal medicine physician records in North Carolina

James Matthew Brennan, M.D. is one of 4,056 internal medicine physician records with a practice address in North Carolina. 82% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2008, is newer than 57% of them.

  • NPI issued2008 · 57% of these records are older, 39% newer
  • In a Medicare fileYes · 82% of these records are
  • In the CMS Doctors and Clinicians fileYes · 67% of these records are
  • Graduated2003 · median 2004 among the 2,706 with a school on file
  • Record last updated2021 · 48% of these records were not updated in five years or more

Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 207R00000X and a North Carolina practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).

380 internal medicine physician records list a practice address in Durham

They are 380 of the 13,451 NPPES records with a practice address in Durham, and 4,056 internal medicine physician records in North Carolina.

The 8 internal medicine physician records with the nearest ZIP codes

  1. Martha Adams, M.D.Durham, NC 277101073606018
  2. Swati Agrawal, M.D.Durham, NC 277101922191188
  3. Cheryl Baker, MDDurham, NC 277101356430813
  4. Richard Frothingham, M.D.Durham, NC 277101912088493
  5. David Gallagher, MDDurham, NC 277101376575746
  6. Rania KazanDurham, NC 277101588748495
  7. James Kelly, MD, MBADurham, NC 277101922004191
  8. Mary Klotman, MDDurham, NC 277101003846411

Common questions

What is James Matthew Brennan, M.D.'s NPI number?

James Matthew Brennan, M.D.'s National Provider Identifier (NPI) is 1164689105, issued on May 19, 2008. An NPI identifies a provider in billing; it is not a license.

Where is James Matthew Brennan, M.D. located?

The NPPES record lists a practice address at 1821 Hillandale RD Suite 25C, Durham, NC, 27710. Phone: (919) 970-7773. Providers update this record themselves, so call before visiting.

How can I verify James Matthew Brennan, M.D.'s license?

NPPES lists North Carolina license number 135846, as entered by the provider. Search the North Carolina Medical Board at https://portal.ncmedboard.org/verification/search.aspx. The NPPES record confirms identity only; the state search shows license status, expiration and public orders.

How much does James Matthew Brennan, M.D. prescribe under Medicare Part D?

In 2024, James Matthew Brennan, M.D. had 7,956 Medicare Part D claims for 1,062 beneficiaries; the average among internal medicine physician prescribers was 3,176. Part D covers Medicare prescriptions only.

Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.

Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.