NPPES file of Aug 9, 2026

James Brennen Byrne, M.D.

Retina Specialist (Ophthalmology) Physician · Huntsville, AL

James Brennen Byrne, M.D. is a retina specialist (ophthalmology) physician with a practice address in Huntsville, Alabama, and NPI 1831128388, issued on Jun 30, 2006. Check the license (Alabama 12006, as entered in NPPES) on the Alabama Board of Medical Examiners; the Medicare figures below come from public CMS files.

Record from CMS NPPES, file of Aug 9, 2026 · Medicare files 2023 and 2024 · method · Verify with CMS →

NPPES recordNPPES file of Aug 9, 2026
1831128388
Name
James Brennen Byrne
Credential
M.D.
Primary taxonomy
Retina Specialist (Ophthalmology) Physician 207WX0107X
License number
12006 AL
Self-reported in NPPES; status is on the state search
Practice location
401 Meridian St N, Huntsville, AL 35801
Phone
(256) 539-8851
Enumerated
Jun 30, 2006
Record last updated
Oct 18, 2019 (not updated in 7 years: call before relying on the address or phone)
Fax
(256) 534-7203
Medicaid ID
051550324 AL
Medicare enrollment
Enrolled (PECOS I20090428000353); accepts Medicare assignment
Medical or professional school
University Of Miami, Lm Miller School Of Medicine, 1982
Entity
Type 1 · individual
Public record from CMS NPPES (open it on the CMS NPI Registry). Enrollment, assignment, school and telehealth: CMS Doctors and Clinicians file, Aug 2026. A record is not a license: verify it with the state board.
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Also registered at 401 Meridian St N

A shared address usually means a shared clinic or building; it does not show who employs whom.

  1. Donald Derivaux, MDOphthalmology Physician1538145594
  2. Heather Flores, NPFamily Nurse Practitioner1275031973
  3. Darren Malone, MDOphthalmology Physician1326263344
  4. Nancy Medeiros, M.D.Retina Specialist (Ophthalmology) Physician1427086404
  5. Tarek Persaud, M.D.Retina Specialist (Ophthalmology) Physician1073578589
  6. Edgar Ready, M.D.Retina Specialist (Ophthalmology) Physician1932136355

Verify James Brennen Byrne in five checks

  1. 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
  2. 2LicenseActive license and public ordersAlabama Board of Medical Examiners
    Search for license 12006
    Check the board
  3. 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
  4. 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
  5. 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
Open the Alabama license search

PlainDoctor does not match the HHS-OIG exclusion list to individual records: most entries carry no NPI. Search the OIG exclusion list by name.

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52% more Medicare Part D claims than the average retina specialist (ophthalmology) physician in 2024

943 Medicare Part D claims for 316 beneficiaries, against an average of 620 among the 1,449 providers of this specialty who prescribed in Part D. Brand-name drugs were 34% of claims. 39 claims were for opioids.

  1. James Byrne943
  2. Specialty average620

Most prescribed

  1. Prednisolone Acetate227 claims
  2. Ketorolac Tromethamine148 claims
  3. Dorzolamide-Timolol141 claims
  4. Latanoprost123 claims
  5. Gentamicin Sulfate51 claims
  6. Timolol Maleate47 claims

Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.

The practice group's MIPS final score for 2023 (Medicare payment program): 100 of 100

The Merit-based Incentive Payment System score is reported for the practice group, not for one clinician alone. Four categories are weighted into the final score; the average among 454,083 clinicians with a measured score was 83.5.

  1. Qualityout of 100 · 30% of the final score100.0
  2. Costnot scored (reweighted)
  3. Promoting interoperabilitynot scored (reweighted)
  4. Improvement activities40 of 40 points · 15%100.0

Source: CMS Quality Payment Program, MIPS performance year 2023, group reporting; category weights for 2023 (qpp.cms.gov).

Industry payments in 2024: $50.18

3 payments; by number, the most common kind was food and beverage; the largest payer was Alimera Sciences, Inc. The 1,253 providers of this specialty with any payment received $7,667.49 on average. Payments are reported by manufacturers, not by the provider, and are not a sign of wrongdoing.

  1. James Byrne$50.18
  2. Specialty average$7,667.49

Source: CMS Open Payments, program year 2024 (openpaymentsdata.cms.gov); average among providers of this specialty with at least one payment.

Bills Medicare through one group practice

  1. Retina Specialists OF North Alabama, LLCHuntsville, AL

Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).

James Brennen Byrne among 21 retina specialist (ophthalmology) physician records in Alabama

James Brennen Byrne, M.D. is one of 21 retina specialist (ophthalmology) physician records with a practice address in Alabama. 100% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2006, is newer than 5% of them.

  • NPI issued2006 · 5% of these records are older, 38% newer
  • In a Medicare fileYes · 100% of these records are
  • In the CMS Doctors and Clinicians fileYes · 95% of these records are
  • Graduated1982 · median 2002 among the 20 with a school on file
  • Record last updated2019 · 71% of these records were not updated in five years or more

Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 207WX0107X and a Alabama practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).

Retina Specialist (Ophthalmology) Physician providers in Alabama

There are 21 retina specialist (ophthalmology) physician records in Alabama.

The 8 retina specialist (ophthalmology) physician records with the nearest ZIP codes

  1. Nancy Medeiros, M.D.Huntsville, AL 358011427086404
  2. Tarek Persaud, M.D.Huntsville, AL 358011073578589
  3. Edgar Ready, M.D.Huntsville, AL 358011932136355
  4. Vikram Saini, M.D.Huntsville, AL 358011710206719
  5. Alexander Talalight, MDHuntsville, AL 358011700094661
  6. Scott Dorin, M.D.Florence, AL 356301588609960
  7. Edward Parma, M.D.Montgomery, AL 361111740219294
  8. Andrew Hsia, MDMontgomery, AL 361171316034259

Common questions

What is James Brennen Byrne, M.D.'s NPI number?

James Brennen Byrne, M.D.'s National Provider Identifier (NPI) is 1831128388, issued on Jun 30, 2006. An NPI identifies a provider in billing; it is not a license.

Where is James Brennen Byrne, M.D. located?

The NPPES record lists a practice address at 401 Meridian St N, Huntsville, AL, 35801. Phone: (256) 539-8851. Providers update this record themselves, so call before visiting.

How can I verify James Brennen Byrne, M.D.'s license?

NPPES lists Alabama license number 12006, as entered by the provider. Search the Alabama Board of Medical Examiners at https://www.albme.gov/. The NPPES record confirms identity only; the state search shows license status, expiration and public orders.

How much does James Brennen Byrne, M.D. prescribe under Medicare Part D?

In 2024, James Brennen Byrne, M.D. had 943 Medicare Part D claims for 316 beneficiaries; the average among retina specialist (ophthalmology) physician prescribers was 620. Part D covers Medicare prescriptions only.

What is James Brennen Byrne, M.D.'s MIPS final score?

The 2023 MIPS final score is 100 of 100, reported for the practice group. The average among 454,083 clinicians with a measured score was 83.5.

Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.

Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.