Karen Melinda Isaacs, MD
Family Medicine Physician · Greer, SC
Karen Melinda Isaacs, MD is a family medicine physician with a practice address in Greer, South Carolina, and NPI 1457589533, issued on Jun 26, 2009. Check the license (South Carolina 93966, as entered in NPPES) on the South Carolina Board of Medical Examiners; the Medicare figures below come from public CMS files.
- Name
- Karen Melinda Isaacs
- Credential
- MD
- Primary taxonomy
- Family Medicine Physician 207Q00000X
- License numbers
- 93966 SC
201101212 NC
Self-reported in NPPES; status is on the state search - Practice location
- 109 Physicians Dr, Greer, SC 29650
- Phone
- (864) 797-9150
- Enumerated
- Jun 26, 2009
- Record last updated
- Jun 23, 2025
- Fax
- (864) 797-9155
- Medicare enrollment
- Enrolled (PECOS I20250428004266); accepts Medicare assignment
- Medical or professional school
- Wake Forest University School Of Medicine, 2009
- Entity
- Type 1 · individual
8 nearest family medicine physician records → All 2,700 in South Carolina → Look up another NPI →
Also registered at 109 Physicians Dr
A shared address usually means a shared clinic or building; it does not show who employs whom.
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- Marjorie AddonizioStudent in an Organized Health Care Education/Training Program1417697566
- Amna Ahmed, MDNeurology Physician1215788310
Verify Karen Melinda Isaacs in five checks
- 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
- 2LicenseActive license and public ordersSouth Carolina Board of Medical Examiners
Search for license 93966Check the board - 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
- 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
- 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
76% fewer Medicare Part D claims than the average family medicine physician in 2024
863 Medicare Part D claims for 153 beneficiaries, against an average of 3,544 among the 117,163 providers of this specialty who prescribed in Part D. 23 claims were for opioids.
Most prescribed
- Levothyroxine Sodium35 claims
- Gabapentin33 claims
- Atorvastatin Calcium31 claims
- Metoprolol Succinate23 claims
- Sertraline Hcl20 claims
- Omeprazole19 claims
Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.
Bills Medicare through one group practice
- Prisma Health University Medical GroupGreer, SC
Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).
Karen Melinda Isaacs among 2,700 family medicine physician records in South Carolina
Karen Melinda Isaacs, MD is one of 2,700 family medicine physician records with a practice address in South Carolina. 78% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2009, is newer than 56% of them.
- NPI issued2009 · 56% of these records are older, 42% newer
- In a Medicare fileYes · 78% of these records are
- In the CMS Doctors and Clinicians fileYes · 61% of these records are
- Graduated2009 · median 2006 among the 1,638 with a school on file
- Record last updated2025 · 50% of these records were not updated in five years or more
Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 207Q00000X and a South Carolina practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).
66 family medicine physician records list a practice address in Greer
They are 66 of the 1,131 NPPES records with a practice address in Greer, and 2,700 family medicine physician records in South Carolina.
All 2,700 in South Carolina → Every provider in Greer → Family Medicine Physician nationwide →
The 8 family medicine physician records with the nearest ZIP codes
- Jack Brunson, M.D.Greer, SC 296501316918253
- Maria Frisch, MDGreer, SC 296501639181662
- Allen Gamble, D.O.Greer, SC 296501265493605
- Rebecca Haskill-Strowd, MDGreer, SC 296501619995065
- Benjamin Hester, M.D.Greer, SC 296501538225206
- David Hudson, M.D.Greer, SC 296501104897891
- Clanford Johnson, M.D.Greer, SC 296501750342879
- Frances Kunda, MDGreer, SC 296501609852391
Common questions
What is Karen Melinda Isaacs, MD's NPI number?
Karen Melinda Isaacs, MD's National Provider Identifier (NPI) is 1457589533, issued on Jun 26, 2009. An NPI identifies a provider in billing; it is not a license.
Where is Karen Melinda Isaacs, MD located?
The NPPES record lists a practice address at 109 Physicians Dr, Greer, SC, 29650. Phone: (864) 797-9150. Providers update this record themselves, so call before visiting.
How can I verify Karen Melinda Isaacs, MD's license?
NPPES lists South Carolina license number 93966, as entered by the provider. Search the South Carolina Board of Medical Examiners at https://verify.llronline.com/LicLookup/Med/Med.aspx?div=22. The NPPES record confirms identity only; the state search shows license status, expiration and public orders.
How much does Karen Melinda Isaacs, MD prescribe under Medicare Part D?
In 2024, Karen Melinda Isaacs, MD had 863 Medicare Part D claims for 153 beneficiaries; the average among family medicine physician prescribers was 3,544. Part D covers Medicare prescriptions only.
Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.
Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.