NPPES file of Aug 9, 2026

Karen J. Santiago Rios, M.D.

Hematology & Oncology Physician · Cidra Puerto Rico, PR

Karen J. Santiago Rios, M.D. is a hematology & oncology physician with a practice address in Cidra Puerto Rico, Puerto Rico, and NPI 1396846119, issued on Sep 26, 2006. Check the license (Puerto Rico 16015, as entered in NPPES) with the Puerto Rico board that licenses this profession; the Medicare figures below come from public CMS files.

Record from CMS NPPES, file of Aug 9, 2026 · Medicare files 2024 · method · Verify with CMS →

NPPES recordNPPES file of Aug 9, 2026
1396846119
Name
Karen J. Santiago Rios
Credential
M.D.
Primary taxonomy
Hematology & Oncology Physician 207RH0003X
License number
16015 PR
Self-reported in NPPES; status is on the state search
Practice location
102 Avenida Industrial EL Jibaro, Cidra Puerto Rico, PR 00739
Phone
(787) 637-5715
Enumerated
Sep 26, 2006
Record last updated
Feb 11, 2015 (not updated in 11 years: call before relying on the address or phone)
Fax
(787) 739-9922
Medicare enrollment
Enrolled (PECOS I20110401000553); accepts Medicare assignment
Medical or professional school
Ponce School Of Medicine, 2002
Entity
Type 1 · individual
Public record from CMS NPPES (open it on the CMS NPI Registry). Enrollment, assignment, school and telehealth: CMS Doctors and Clinicians file, Aug 2026. A record is not a license: verify it with the state board.
Download card Updates feed

Verify Karen J. Santiago Rios in five checks

  1. 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
  2. 2LicenseActive license and public ordersWhich Puerto Rico board licenses this profession
    Search for license 16015
    Check the board
  3. 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
  4. 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
  5. 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
Find the Puerto Rico license search

PlainDoctor does not match the HHS-OIG exclusion list to individual records: most entries carry no NPI. Search the OIG exclusion list by name.

Is this page about you? You can ask us to correct, restrict or remove it: how.

72% fewer Medicare Part D claims than the average hematology & oncology physician in 2024

248 Medicare Part D claims for 52 beneficiaries, against an average of 877 among the 10,784 providers of this specialty who prescribed in Part D. Brand-name drugs were 23% of claims.

  1. Karen Santiago Rios248
  2. Specialty average877

Most prescribed

  1. Anastrozole75 claims
  2. Dexamethasone24 claims
  3. Imbruvica24 claims
  4. Hydroxyurea15 claims
  5. Ondansetron Hcl13 claims

Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.

Industry payments in 2024: $2,571.18

110 payments; by number, the most common kind was food and beverage; the largest payer was AstraZeneca Pharmaceuticals LP. The 8,560 providers of this specialty with any payment received $7,481.41 on average. Payments are reported by manufacturers, not by the provider, and are not a sign of wrongdoing.

  1. Karen Santiago Rios$2,571.18
  2. Specialty average$7,481.41

Source: CMS Open Payments, program year 2024 (openpaymentsdata.cms.gov); average among providers of this specialty with at least one payment.

Bills Medicare through one group practice

  1. Caribbean Cancer Care Services LLCSan Juan, PR

Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).

Karen J. Santiago Rios among 134 hematology & oncology physician records in Puerto Rico

Karen J. Santiago Rios, M.D. is one of 134 hematology & oncology physician records with a practice address in Puerto Rico. 91% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2006, is newer than 16% of them.

  • NPI issued2006 · 16% of these records are older, 51% newer
  • In a Medicare fileYes · 91% of these records are
  • In the CMS Doctors and Clinicians fileYes · 73% of these records are
  • Graduated2002 · median 2001 among the 98 with a school on file
  • Record last updated2015 · 63% of these records were not updated in five years or more

Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 207RH0003X and a Puerto Rico practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).

Hematology & Oncology Physician providers in Puerto Rico

There are 134 hematology & oncology physician records in Puerto Rico.

The 8 hematology & oncology physician records with the nearest ZIP codes

  1. Luz Cortes, MDFajardo, PR 007381205897352
  2. Josselyn Molina Avila, M.D.Fajardo, PR 007381962818872
  3. Carlos Tejeda, M.D.Fajardo, PR 007381366574725
  4. Doris Colon, M.D.Cayey, PR 007361477545929
  5. Alicia Mendez, M.D.Cayey, PR 007361164414686
  6. Omayra Reyes Santiago, M.D.Cayey, PR 007361124287313
  7. Jose Cangiano, M.D.Ponce, PR 007301114961091
  8. Amy Cabrera, MDCanovanas, PR 007291831454123

Common questions

What is Karen J. Santiago Rios, M.D.'s NPI number?

Karen J. Santiago Rios, M.D.'s National Provider Identifier (NPI) is 1396846119, issued on Sep 26, 2006. An NPI identifies a provider in billing; it is not a license.

Where is Karen J. Santiago Rios, M.D. located?

The NPPES record lists a practice address at 102 Avenida Industrial EL Jibaro, Cidra Puerto Rico, PR, 00739. Phone: (787) 637-5715. Providers update this record themselves, so call before visiting.

How can I verify Karen J. Santiago Rios, M.D.'s license?

NPPES lists Puerto Rico license number 16015, as entered by the provider. Search the Puerto Rico board that licenses this profession; the NPPES record confirms identity only.

How much does Karen J. Santiago Rios, M.D. prescribe under Medicare Part D?

In 2024, Karen J. Santiago Rios, M.D. had 248 Medicare Part D claims for 52 beneficiaries; the average among hematology & oncology physician prescribers was 877. Part D covers Medicare prescriptions only.

Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.

Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.