2026 NPPES data Hematology & Oncology Physician NPI 1366860496 D.O.
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Krista Isaac, D.O.

Hematology & Oncology Physician in Charlottesville, Virginia.

This profile is drawn from the federal National Provider Identifier Registry (CMS NPPES), which lists more than 7 million U.S. healthcare providers - including 11,232 in Hematology & Oncology Physician, and covers specialty classification, practice address, and Medicare Part D prescribing data when reported. According to CMS, every field reflects the provider's official federal registration, see our methodology.

Federal data, no proprietary rating. We show these CMS records as-is - no composite score, no star rating, no editorial opinion layered on top.
Prescribing volume
491
Medicare Part D claims · 130 beneficiaries · Hematology & Oncology Physician avg: 847
Generic prescribing
75%
generic claims · 25% brand-name · higher generic rates reduce patient out-of-pocket costs
MIPS score
93.2/100
▲ 10 pts above national avg 83.1 · Exceptional
Industry payments
$2.5K
119 payments · CMS Open Payments (Sunshine Act)
Compiled from official public sources by the PlainDoctor editorial team.

What the federal data shows

Krista Isaac, D.O. reported a CMS MIPS final score of 93.2/100 - above the 83.1 national average - and filed 491 Medicare Part D claims in 2023.

93.2/100
MIPS score · +10 vs avg
491
Part D claims, 2023
75%
generic prescribing
Likely
board-certified (heuristic)

Every figure on this page comes straight from federal CMS records (NPPES, Medicare Part D, MIPS, Open Payments) - no proprietary rating or editorial opinion is applied.

Krista Isaac, D.O.'s MIPS score vs every scored U.S. clinician

CMS Merit-based Incentive Payment System (MIPS) final score, 2023, the federal quality measure

93 Top 29% higher than 71% of 477,587 scored providers

0–10: 8,684 scored providers (2%). Below this entry. 10–20: 3,008 scored providers (1%). Below this entry. 20–30: 3,069 scored providers (1%). Below this entry. 30–40: 2,746 scored providers (1%). Below this entry. 40–50: 2,928 scored providers (1%). Below this entry. 50–60: 5,882 scored providers (1%). Below this entry. 60–70: 13,906 scored providers (3%). Below this entry. 70–80: 118,074 scored providers (25%). Below this entry. 80–90: 129,887 scored providers (27%). Below this entry. 90+: 189,403 scored providers (40%). This entry sits in this band. This provider 0 100 every MIPS-scored clinician, bucketed by value

Each bar is a band; taller bars hold more scored providers. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source CMS Merit-based Incentive Payment System (MIPS) · 2023

Where Krista Isaac, D.O. sits

This provider among hematology & oncology physician peers

Across the 4,233 hematology & oncology physician providers who report both Medicare Part D prescribing and a MIPS quality score, Krista Isaac, D.O. writes more Part D claims than 36% of them and scores higher on MIPS quality than 71% - placing this provider in the lower-volume, high-quality quadrant. Volume reflects patient-panel size and specialty, not quality; the two axes are independent.

Part D claim volume vs MIPS quality, by specialty percentile

Lower volume · High qualityHigh volume · High qualityLower volume · Lower qualityHigh volume · Lower quality0255075100024.148.372.496.6Part D claim volume, percentile in specialtyMIPS quality, percentilePart D claim volume, percentile in specialty: 72 · MIPS quality, percentile: 8Part D claim volume, percentile in specialty: 98 · MIPS quality, percentile: 65Part D claim volume, percentile in specialty: 50 · MIPS quality, percentile: 40Part D claim volume, percentile in specialty: 38 · MIPS quality, percentile: 78Part D claim volume, percentile in specialty: 22 · MIPS quality, percentile: 23Part D claim volume, percentile in specialty: 93 · MIPS quality, percentile: 92Part D claim volume, percentile in specialty: 17 · MIPS quality, percentile: 60Part D claim volume, percentile in specialty: 58 · MIPS quality, percentile: 80Part D claim volume, percentile in specialty: 25 · MIPS quality, percentile: 92Part D claim volume, percentile in specialty: 83 · MIPS quality, percentile: 73Part D claim volume, percentile in specialty: 5 · MIPS quality, percentile: 25Part D claim volume, percentile in specialty: 88 · MIPS quality, percentile: 35Part D claim volume, percentile in specialty: 7 · MIPS quality, percentile: 57Part D claim volume, percentile in specialty: 18 · MIPS quality, percentile: 47Part D claim volume, percentile in specialty: 20 · MIPS quality, percentile: 30Part D claim volume, percentile in specialty: 42 · MIPS quality, percentile: 10Part D claim volume, percentile in specialty: 3 · MIPS quality, percentile: 75Part D claim volume, percentile in specialty: 67 · MIPS quality, percentile: 2Part D claim volume, percentile in specialty: 77 · MIPS quality, percentile: 33Part D claim volume, percentile in specialty: 65 · MIPS quality, percentile: 92Part D claim volume, percentile in specialty: 52 · MIPS quality, percentile: 47Part D claim volume, percentile in specialty: 33 · MIPS quality, percentile: 90Part D claim volume, percentile in specialty: 45 · MIPS quality, percentile: 40Part D claim volume, percentile in specialty: 85 · MIPS quality, percentile: 0Part D claim volume, percentile in specialty: 55 · MIPS quality, percentile: 83Part D claim volume, percentile in specialty: 87 · MIPS quality, percentile: 37Part D claim volume, percentile in specialty: 60 · MIPS quality, percentile: 92Part D claim volume, percentile in specialty: 23 · MIPS quality, percentile: 38Part D claim volume, percentile in specialty: 80 · MIPS quality, percentile: 47Part D claim volume, percentile in specialty: 92 · MIPS quality, percentile: 20Part D claim volume, percentile in specialty: 15 · MIPS quality, percentile: 72Part D claim volume, percentile in specialty: 30 · MIPS quality, percentile: 82Part D claim volume, percentile in specialty: 27 · MIPS quality, percentile: 87Part D claim volume, percentile in specialty: 0 · MIPS quality, percentile: 68Part D claim volume, percentile in specialty: 82 · MIPS quality, percentile: 15Part D claim volume, percentile in specialty: 28 · MIPS quality, percentile: 3Part D claim volume, percentile in specialty: 70 · MIPS quality, percentile: 77Part D claim volume, percentile in specialty: 75 · MIPS quality, percentile: 53Part D claim volume, percentile in specialty: 57 · MIPS quality, percentile: 17Part D claim volume, percentile in specialty: 90 · MIPS quality, percentile: 92Part D claim volume, percentile in specialty: 78 · MIPS quality, percentile: 45Part D claim volume, percentile in specialty: 13 · MIPS quality, percentile: 28Part D claim volume, percentile in specialty: 48 · MIPS quality, percentile: 7Part D claim volume, percentile in specialty: 33 · MIPS quality, percentile: 88Part D claim volume, percentile in specialty: 43 · MIPS quality, percentile: 52Part D claim volume, percentile in specialty: 95 · MIPS quality, percentile: 70Part D claim volume, percentile in specialty: 10 · MIPS quality, percentile: 53Part D claim volume, percentile in specialty: 2 · MIPS quality, percentile: 12Part D claim volume, percentile in specialty: 37 · MIPS quality, percentile: 58Part D claim volume, percentile in specialty: 32 · MIPS quality, percentile: 12Part D claim volume, percentile in specialty: 73 · MIPS quality, percentile: 5Part D claim volume, percentile in specialty: 8 · MIPS quality, percentile: 43Part D claim volume, percentile in specialty: 100 · MIPS quality, percentile: 85Part D claim volume, percentile in specialty: 68 · MIPS quality, percentile: 20Part D claim volume, percentile in specialty: 97 · MIPS quality, percentile: 18Part D claim volume, percentile in specialty: 47 · MIPS quality, percentile: 32Part D claim volume, percentile in specialty: 63 · MIPS quality, percentile: 67Part D claim volume, percentile in specialty: 53 · MIPS quality, percentile: 63Part D claim volume, percentile in specialty: 12 · MIPS quality, percentile: 27Part D claim volume, percentile in specialty: 62 · MIPS quality, percentile: 92Krista Isaac, D.O.-Part D claim volume, percentile in specialty: 36 · MIPS quality, percentile: 71
Part D claim volume vs MIPS quality, by specialty percentile

Each dot is one hematology & oncology physician peer from a representative sample of 60; the gold marker is Krista Isaac, D.O.. Source: CMS Medicare Part D Prescriber data and the CMS Merit-based Incentive Payment System, 2023.

Board certification likely (heuristic, not verified)

Krista Isaac, D.O. practices in an ABMS-board-eligible specialty and shows active CMS Medicare participation + MIPS quality reporting + 1 hospital affiliation - signals consistent with board-certified status. For verified board certification, see CertificationMatters.org (the official ABMS public lookup).

What does the federal data show about Krista Isaac, D.O.?

High performer (top quartile)

NPI registry status

Active

Issued 04/05/2014

NPI 1366860496

Primary specialty

Hematology & Oncology Physician

Mid-sized

11,232 US NPIs in this specialty

Medicare Part D claims

491 42% vs specialty avg

2023 prescription claims

Specialty avg: 847

MIPS final score

93.2/100 10.1 pts vs avg

Exceptional band

vs 83.1 national avg

Specialty distribution in Virginia

How Hematology & Oncology Physician compares to other specialties among Virginia providers

Virginia providers
Behavior Technician - 5.2%Behavior Technician5.2%Clinical Social Worker - 5.1%Clinical Social Worker5.1%Student in an Organized Health Care Education/Training Program - 4.7%Student in an Organized Health Care Education/Training Program4.7%Physical Therapist - 4.6%Physical Therapist4.6%Pharmacist - 4.5%Pharmacist4.5%Professional Counselor - 4%Professional Counselor4%Hematology & Oncology Physician - 0.2%Hematology & Oncology Physician0.2%
Largest specialties in Virginia (% of in-state providers)

Medicare quality performance, MIPS

Krista Isaac, D.O.'s 2023 MIPS final score plotted against the Hematology & Oncology Physician national average

High performer (top quartile)
MIPS Final Score
93.2/100
vs 83.1 national avg · 2023 performance year

MIPS final score (Hematology & Oncology Physician) - 93.2/100 vs national avg 83.1

0%100%National avg83%93.2%
MIPS final score (Hematology & Oncology Physician) - 93.2/100 vs national avg 83.1
How MIPS and board certification work

The Merit-based Incentive Payment System (MIPS) scores providers 0–100 across four performance categories: Quality, Cost, Promoting Interoperability, and Improvement Activities, weighted under 42 CFR §414.1380. Reporting is voluntary for many small practices, so absence of a MIPS score is not a quality signal.

Board certification through an ABMS or AOA member board signals voluntary post-licensure examination plus continuous Maintenance of Certification cycles. Verify any individual provider's status through certificationmatters.org (ABMS) or osteopathic.org (AOA).

Krista Isaac, D.O. appears in the CMS NPPES registry as a Hematology & Oncology Physician provider holding D.O. credentials at 1215 LEE ST - BOX NUMBER 800716, Charlottesville, VA, 22908, with a listed phone of (434) 924-9333. NPI 1366860496 was issued on 04/05/2014.

Medicare Part D records for calendar year 2023 show 491 prescription claims written by this provider, covering 130 Medicare beneficiaries and totaling roughly $336K in drug spend, split 25% brand-name and 75% generic by claim count, with an opioid prescribing rate of 11.6%. On the CMS Merit-based Incentive Payment System, this provider earned a Final Score of 93.2/100 for the 2023 performance year (Quality 75.1, Cost 98.2), compared with the national average of 83.1.

Hematology & Oncology Physician is a mid-sized specialty nationwide, with 11,232 enrolled providers across 54 states and an average of 847 Part D claims per prescriber, so the context for interpreting these metrics differs meaningfully from a primary-care baseline.

Important: PlainDoctor is a directory of publicly available government data, not medical advice, a malpractice database, or a quality rating. Inclusion here does not imply a recommendation, and absence of complaints or sanctions on this page does not mean none exist, always verify credentials through the NPPES NPI Registry, your state medical board, and the ABMS or AOA before making healthcare decisions.

Practice Address

1215 LEE ST - BOX NUMBER 800716
Charlottesville, VA 22908

Provider Details

NPI 1366860496
Specialty Hematology & Oncology Physician
Credentials D.O.
Gender Female
NPI Issued 04/05/2014

CMS Quality Score (MIPS)

Merit-based Incentive Payment System (MIPS) scores from CMS, 2023 performance year.

93.1879
Final Score
Avg: 83.1
75.124
Quality
98.246
Cost
94
Promoting Interoperability

Reporting: subgroup

Hospital and facility affiliations

Facilities where Krista Isaac, D.O. bills Medicare from. Star ratings (1-5) are CMS Hospital Compare's "Hospital overall rating" - a composite of mortality, readmission, patient experience, safety, timely care, and efficient use of medical imaging measures. Source: CMS Care Compare.

Alliance Cancer Specialists P.C.
Langhorne, PA

Affiliations sourced from CMS Doctors and Clinicians National Downloadable File; hospital ratings from CMS Hospital General Information dataset (cross-referenced by facility name + state).

Industry payments received (2024) - CMS Open Payments transparency data

The federal Physician Payments Sunshine Act (part of the Affordable Care Act) requires drug and medical-device manufacturers + group purchasing organizations to publicly report payments and other transfers of value to physicians and teaching hospitals. The data below covers 2024 for Krista Isaac, D.O.. Source: openpaymentsdata.cms.gov.

Total received

$2.5K

Largest payer

Novartis Pharmaceuticals Corporation

Most common payment type

Food and Beverage

Industry payments are not necessarily indicators of bias, they include research funding, consulting fees for evidence-based work, royalties for inventions, food at conferences, and similar items. The disclosure exists for transparency. Read our methodology for how we interpret this data.

Brand vs generic prescribing mix · Above average

Krista Isaac, D.O. - brand share 25.0%
Hematology & Oncology Physician average

25% brand-name claims vs 75% generic, on 491 2023 Medicare Part D claims.

The federal Medicare Part D Generic Dispensing Rate national benchmark sits near 90% generic / 10% brand for primary-care prescribers, per CMS Office of the Actuary 2024 estimates. Higher brand share is common in specialty prescribing where generic equivalents are not available.

Medicare Part D Prescribing Data

CMS Medicare Part D prescriber-level data for calendar year 2023.

491
Total Claims
$336K
Total Drug Cost
130
Medicare Beneficiaries

Prescribing Breakdown

30-Day Fills
668
Total Day Supply
16,338
Brand vs Generic
25% brand / 75% generic
Brand Drug Cost
$317K
Generic Drug Cost
$19K
Opioid Claims
57 (11.6% rate)
Antibiotic Claims
31

Patient Demographics

Average Patient Age
73.1 years
Avg HCC Risk Score
1.84
Gender Split
65% female / 35% male
Age Distribution
<65: 14, 65-74: 57, 75-84: 45, 85+: 14

Top Prescribed Drugs (Medicare Part D)

Top drugs by claim count for calendar year 2023. Based on Medicare Part D data only.

What Krista Isaac, D.O. prescribes most

Top Medicare Part D drugs by claim count, 2023

claims
Source CMS Medicare Part D Prescriber Public Use File As of 2023
Drug Claims
Eliquis
Apixaban
67
Letrozole
39
Oxycodone Hcl
36
Tamoxifen Citrate
23
Xarelto
Rivaroxaban
23
Anastrozole
21
Ondansetron Odt
Ondansetron
21
Prednisone
21
Dexamethasone
19
Granisetron Hcl
16

* Counts below 11 are suppressed by CMS for patient privacy. Generic names shown where available from CMS Part D data.

Hematology & Oncology Physician Overview

How Krista Isaac, D.O. fits within the Hematology & Oncology Physician landscape nationally.

11,232
Hematology & Oncology Physician Providers in US
54
States with Hematology & Oncology Physician
847
Avg Claims per Provider

Krista Isaac, D.O.'s 491 claims are below the specialty average of 847.

Nearby Hematology & Oncology Physician Providers in Virginia

Other clinicians with the same primary specialty enrolled in Virginia, drawn from the same CMS NPPES roster as Isaac.

Compare Hematology & Oncology Physician nationally: see state-by-state distribution →

Before you book an appointment

Use this federal record as your verification checklist, not as a recommendation.

  • Confirm the NPI record is current in the official CMS registry, providers update their own NPPES details, and moves can lag. Verify this NPI
  • Check the active license and any disciplinary history with the Virginia medical board, federal registration is not a license check. Credential verification guide
  • Weigh a second option: compare this provider with a nearby Hematology & Oncology Physician peer on Medicare volume and prescribing patterns. Compare providers

Medicare Part D and MIPS figures describe practice patterns in federal programs only, they are not quality ratings, and PlainDoctor does not rate, rank, or recommend providers.

Frequently Asked Questions

What is Krista Isaac, D.O.'s specialty?
Krista Isaac, D.O. specializes in Hematology & Oncology Physician and practices in Charlottesville, Virginia. Credentials: D.O..
How much does Krista Isaac, D.O. prescribe under Medicare Part D?
In 2023, Krista Isaac, D.O. wrote 491 Medicare Part D claims totaling $336K in drug costs for 130 beneficiaries.
What is Krista Isaac, D.O.'s Medicare quality score?
Krista Isaac, D.O. has a CMS MIPS Final Score of 93.2/100 (Quality: 75.1, Cost: 98.2). The national average MIPS Final Score is 83.1. Source: CMS Merit-based Incentive Payment System (MIPS) 2023.
Where is Krista Isaac, D.O. located?
Krista Isaac, D.O. is located at 1215 LEE ST - BOX NUMBER 800716, Charlottesville, VA, 22908. Phone: (434) 924-9333.
What is Krista Isaac, D.O.'s NPI number?
Krista Isaac, D.O.'s National Provider Identifier (NPI) is 1366860496, issued on 04/05/2014.
Does Krista Isaac, D.O. prescribe more brand-name or generic drugs?
Krista Isaac, D.O.'s prescribing is 25% brand-name and 75% generic drugs by claim count, with $317K in brand drug costs.
Does Krista Isaac, D.O. prescribe opioids?
Yes, Krista Isaac, D.O. had 57 opioid claims in 2023 with an opioid prescribing rate of 11.6%.
How many Hematology & Oncology Physician providers are there in the US?
There are 11,232 Hematology & Oncology Physician providers across 54 states in the US. The average Hematology & Oncology Physician provider writes 847 Medicare Part D claims per year.
What drugs does Krista Isaac, D.O. prescribe most often?
Based on 2023 Medicare Part D data, Krista Isaac, D.O.'s most frequently prescribed drugs include Eliquis, Letrozole, Oxycodone Hcl. This reflects Medicare Part D prescriptions only and does not include commercial insurance or other payer types.
Does Krista Isaac, D.O. accept Medicare?
Krista Isaac, D.O. appears in CMS Medicare data with 491 Part D claims and 130 Medicare beneficiaries in 2023. Contact the provider's office directly to confirm current Medicare enrollment and accepted plans.
How can I verify Krista Isaac, D.O.'s credentials?
Krista Isaac, D.O.'s NPI is 1366860496 with credentials D.O.. You can verify this through the NPPES NPI Registry, check state medical board records, and confirm board certification through the ABMS or AOA.

Data Sources

View source datasets and methodology notes
Provider Directory
CMS National Plan and Provider Enumeration System (NPPES), download.cms.gov/nppes, updated monthly. Contains NPI, specialty, credentials, and practice location.
Specialty Classification
NUCC Health Care Provider Taxonomy (nucc.org), the industry standard for classifying provider specialties in Medicare and Medicaid billing.
Prescribing Data
CMS Medicare Part D Prescriber Public Use File (2023). Includes claims, drug costs, beneficiaries, and opioid prescribing rates.
Quality Performance
CMS Merit-based Incentive Payment System (MIPS) - 2023 performance year.
Limitations
Provider data is self-reported to CMS. Prescribing data reflects Medicare Part D only and does not include commercial insurance, Medicaid, or cash prescriptions. Claims below 11 beneficiaries are suppressed by CMS for privacy.

See our complete data methodology for details on how we collect and process government data.

Data as of April 2026 (NPPES) / 2023 (Medicare Part D). Source: Centers for Medicare & Medicaid Services (CMS).

Disclaimer: Data from CMS NPPES and Medicare Part D. PlainDoctor does not rate or rank providers. Provider information is self-reported and may not be current. Always verify information directly with the provider. About · Methodology

Compiled from official public sources by the PlainDoctor editorial team.

Every figure on PlainDoctor is rendered directly from the federal CMS NPPES registry, Medicare Part D, MIPS, and Open Payments records, no number is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of May 2026.