LUIS SANTIAGO-PAGAN, M.D. appears in the CMS NPPES registry as a Ophthalmology Physician provider holding M.D. credentials at 56 CALLE PEDRO ROSARIO, AIBONITO, PR, 00705, with a listed phone of (787) 991-1325. NPI 1427085448 was issued on 06/26/2006. Because NPPES data is self-reported by the provider and refreshed monthly, the address, phone, and specialty reflect what SANTIAGO-PAGAN most recently submitted to CMS rather than a vetted directory listing, which is why patients should always confirm the practice is still at this location before scheduling.

Medicare Part D records for calendar year 2023 show 15,184 prescription claims written by this provider, covering 2,389 Medicare beneficiaries and totaling roughly $1.2 million in drug spend, split 51% brand-name and 49% generic by claim count. These figures capture only Medicare Part D — commercial insurance, Medicaid, and cash-pay prescriptions are not included, and any drug-beneficiary cell under 11 is suppressed by CMS for patient privacy.

Ophthalmology Physician is a mid-sized specialty nationwide, with 22,090 enrolled providers across 56 states and an average of 1,420 Part D claims per prescriber, so the context for interpreting these metrics differs meaningfully from a primary-care baseline. Important: PlainDoctor is a directory of publicly available government data, not medical advice, a malpractice database, or a quality rating. Inclusion here does not imply a recommendation, and absence of complaints or sanctions on this page does not mean none exist — always verify credentials through the NPPES NPI Registry, your state medical board, and the ABMS or AOA before making healthcare decisions.