Mario A. Santiago, M.D.
General Practice Physician · Orlando, FL
Mario A. Santiago, M.D. is a general practice physician with a practice address in Orlando, Florida, and NPI 1215998976, issued on Mar 31, 2006. Check the license (Florida ACN648, as entered in NPPES) on the Florida health license search; the Medicare figures below come from public CMS files.
- Name
- Mario A. Santiago
- Credential
- M.D.
- Primary taxonomy
- General Practice Physician 208D00000X
- License numbers
- ACN648 FL
14652 PR
Self-reported in NPPES; status is on the state search - Practice location
- 737 S Semoran Blvd, Orlando, FL 32807
- Phone
- (321) 247-4960
- Enumerated
- Mar 31, 2006
- Record last updated
- Feb 17, 2026
- Medicaid ID
- 101875500 FL
- Medicare enrollment
- Enrolled (PECOS I20151218001780); accepts Medicare assignment
- Entity
- Type 1 · individual
Also registered at 737 S Semoran Blvd
A shared address usually means a shared clinic or building; it does not show who employs whom.
- Martha Bonett, APRNPrimary Care Nurse Practitioner1427827138
- Daniel Clark, PMHNP-BCPsychiatric/Mental Health Nurse Practitioner1215788682
- Alexsandra King, NPFamily Nurse Practitioner1407388028
- Arelis Rodriguez Caban, M.D.General Practice Physician1467566711
- David Sanjuan, MDGeneral Practice Physician1306270509
- Jonnathan Soltero, ARNPFamily Nurse Practitioner1376068940
Verify Mario A. Santiago in five checks
- 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
- 2LicenseActive license and public ordersFlorida health license search
Search for license ACN648Check the board - 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
- 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
- 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
3.0 times the Medicare Part D claims of the average general practice physician in 2024
9,143 Medicare Part D claims for 821 beneficiaries, against an average of 3,030 among the 8,395 providers of this specialty who prescribed in Part D. Brand-name drugs were 11% of claims. 31 claims were for opioids.
Most prescribed
- Atorvastatin Calcium551 claims
- Amlodipine Besylate360 claims
- Rosuvastatin Calcium347 claims
- Losartan Potassium341 claims
- Metformin Hcl330 claims
- Levothyroxine Sodium309 claims
Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.
Bills Medicare through one group practice
- Centerwell Senior Primary Care FL Inc.Orlando, FL
Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).
General Practice Physician providers in Florida
There are 2,282 general practice physician records in Florida.
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- Jamal Abusuwa, MDOviedo, FL1053310342
- Patrick Abuzeni, MDCoral Gables, FL1295066579
- Annette Acevedo, M.D.Lakeland, FL1932171063
- Armando Acevedo, M.D.Miami, FL1003901893
- Betzy Acevedo, DRA.Kissimmee, FL1184647778
- Gilfredy Acevedo, M.D.Orlando, FL1114997699
Common questions
What is Mario A. Santiago, M.D.'s NPI number?
Mario A. Santiago, M.D.'s National Provider Identifier (NPI) is 1215998976, issued on Mar 31, 2006. An NPI identifies a provider in billing; it is not a license.
Where is Mario A. Santiago, M.D. located?
The NPPES record lists a practice address at 737 S Semoran Blvd, Orlando, FL, 32807. Phone: (321) 247-4960. Providers update this record themselves, so call before visiting.
How can I verify Mario A. Santiago, M.D.'s license?
NPPES lists Florida license number ACN648, as entered by the provider. Search the Florida health license search at https://mqa-internet.doh.state.fl.us/mqasearchservices/healthcareproviders. The NPPES record confirms identity only; the state search shows license status, expiration and public orders.
How much does Mario A. Santiago, M.D. prescribe under Medicare Part D?
In 2024, Mario A. Santiago, M.D. had 9,143 Medicare Part D claims for 821 beneficiaries; the average among general practice physician prescribers was 3,030. Part D covers Medicare prescriptions only.
Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.
Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.