Mario Ernest Serafini, D.O.
Pain Medicine (Anesthesiology) Physician · Charleston, SC
Mario Ernest Serafini, D.O. is a pain medicine (anesthesiology) physician with a practice address in Charleston, South Carolina, and NPI 1225097397, issued on Mar 18, 2006. Check the license (South Carolina 39925, as entered in NPPES) on the South Carolina Board of Medical Examiners; the Medicare figures below come from public CMS files.
- Name
- Mario Ernest Serafini
- Credential
- D.O.
- Primary taxonomy
- Pain Medicine (Anesthesiology) Physician 207LP2900X
- License numbers
- 39925 SC
03200052067 VT
1438 WV
Self-reported in NPPES; status is on the state search - Practice location
- 171 Ashley Ave, Charleston, SC 29425
- Phone
- (843) 792-1414
- Enumerated
- Mar 18, 2006
- Record last updated
- Jul 21, 2022
- Medicaid ID
- 0063453000 WV
- Entity
- Type 1 · individual
8 nearest pain medicine (anesthesiology) physician records → All 64 in South Carolina → Look up another NPI →
Also registered at 171 Ashley Ave
A shared address usually means a shared clinic or building; it does not show who employs whom.
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Verify Mario Ernest Serafini in five checks
- 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
- 2LicenseActive license and public ordersSouth Carolina Board of Medical Examiners
Search for license 39925Check the board - 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
- 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
- 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
The MIPS final score for 2023 (Medicare payment program): 98.1 of 100
The Merit-based Incentive Payment System score is reported for this clinician. Four categories are weighted into the final score; the average among 454,083 clinicians with a measured score was 83.5.
Source: CMS Quality Payment Program, MIPS performance year 2023; category weights for 2023 (qpp.cms.gov).
Mario Ernest Serafini among 64 pain medicine (anesthesiology) physician records in South Carolina
Mario Ernest Serafini, D.O. is one of 64 pain medicine (anesthesiology) physician records with a practice address in South Carolina. 83% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2006, is newer than 8% of them.
- NPI issued2006 · 8% of these records are older, 41% newer
- In a Medicare fileYes · 83% of these records are
- In the CMS Doctors and Clinicians fileNo · 72% of these records are
- Record last updated2022 · 36% of these records were not updated in five years or more
Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 207LP2900X and a South Carolina practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).
Pain Medicine (Anesthesiology) Physician providers in South Carolina
There are 64 pain medicine (anesthesiology) physician records in South Carolina.
All 64 in South Carolina → Every provider in Charleston → Pain Medicine (Anesthesiology) Physician nationwide →
The 8 pain medicine (anesthesiology) physician records with the nearest ZIP codes
- Martin Burke, M.D.Charleston, SC 294251053793588
- Michael Hillegass, M.D.Charleston, SC 294251124225552
- Andrew MendelsonCharleston, SC 294251518329416
- Meron Selassie, MDCharleston, SC 294251932490091
- Russell Seymore, M.D.Charleston, SC 294251881788636
- Arthur Smith, MDCharleston, SC 294251770691719
- Justin Wikle, M.D.Charleston, SC 294251912292152
- Robert Sullivan, M.D.Charleston, SC 294141538368923
Common questions
What is Mario Ernest Serafini, D.O.'s NPI number?
Mario Ernest Serafini, D.O.'s National Provider Identifier (NPI) is 1225097397, issued on Mar 18, 2006. An NPI identifies a provider in billing; it is not a license.
Where is Mario Ernest Serafini, D.O. located?
The NPPES record lists a practice address at 171 Ashley Ave, Charleston, SC, 29425. Phone: (843) 792-1414. Providers update this record themselves, so call before visiting.
How can I verify Mario Ernest Serafini, D.O.'s license?
NPPES lists South Carolina license number 39925, as entered by the provider. Search the South Carolina Board of Medical Examiners at https://verify.llronline.com/LicLookup/Med/Med.aspx?div=22. The NPPES record confirms identity only; the state search shows license status, expiration and public orders.
What is Mario Ernest Serafini, D.O.'s MIPS final score?
The 2023 MIPS final score is 98.1 of 100. The average among 454,083 clinicians with a measured score was 83.5.
Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.
Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.