Mark Louis Wess, M.D.
Internal Medicine Physician · Greenville, SC
Mark Louis Wess, M.D. is an internal medicine physician with a practice address in Greenville, South Carolina, and NPI 1861440042, issued on May 4, 2006. Check the license (South Carolina 35155, as entered in NPPES) on the South Carolina Board of Medical Examiners; the Medicare figures below come from public CMS files.
- Name
- Mark Louis Wess
- Credential
- M.D.
- Primary taxonomy
- Internal Medicine Physician 207R00000X
- License number
- 35155 SC
Self-reported in NPPES; status is on the state search - Practice location
- 3516 Highway 153, Greenville, SC 29611
- Phone
- (864) 729-6626
- Enumerated
- May 4, 2006
- Record last updated
- Mar 25, 2026
- Fax
- (855) 617-4425
- Medicaid ID
- 351559 SC
- Medicare enrollment
- Enrolled (PECOS I20130116000012); accepts Medicare assignment
- Medical or professional school
- University Of Cincinnati College Of Medicine, 1989
- Telehealth
- Offers telehealth (CMS)
- Entity
- Type 1 · individual
8 nearest internal medicine physician records → All 1,881 in South Carolina → Look up another NPI →
Also registered at 3516 Highway 153
A shared address usually means a shared clinic or building; it does not show who employs whom.
- Gerlanda Derr, APRNFamily Nurse Practitioner1205072808
- Maresa Haynes, APRNFamily Nurse Practitioner1447862909
- Zachariah Overby, MDFamily Medicine Physician1497982060
- Nancy Trifilo, ARNPFamily Nurse Practitioner1588615561
Verify Mark Louis Wess in five checks
- 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
- 2LicenseActive license and public ordersSouth Carolina Board of Medical Examiners
Search for license 35155Check the board - 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
- 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
- 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
75% more Medicare Part D claims than the average internal medicine physician in 2024
5,573 Medicare Part D claims for 779 beneficiaries, against an average of 3,176 among the 108,855 providers of this specialty who prescribed in Part D. Brand-name drugs were 11% of claims. 44 claims were for opioids.
Most prescribed
- Rosuvastatin Calcium247 claims
- Amlodipine Besylate245 claims
- Lisinopril225 claims
- Atorvastatin Calcium222 claims
- Gabapentin221 claims
- Levothyroxine Sodium191 claims
Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.
Bills Medicare through one group practice
- Centerwell Senior Primary Care SC PCAnderson, SC
Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).
Mark Louis Wess among 1,881 internal medicine physician records in South Carolina
Mark Louis Wess, M.D. is one of 1,881 internal medicine physician records with a practice address in South Carolina. 81% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2006, is newer than 7% of them.
- NPI issued2006 · 7% of these records are older, 58% newer
- In a Medicare fileYes · 81% of these records are
- In the CMS Doctors and Clinicians fileYes · 60% of these records are
- Graduated1989 · median 2006 among the 1,119 with a school on file
- Record last updated2026 · 46% of these records were not updated in five years or more
Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 207R00000X and a South Carolina practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).
253 internal medicine physician records list a practice address in Greenville
They are 253 of the 10,264 NPPES records with a practice address in Greenville, and 1,881 internal medicine physician records in South Carolina.
All 1,881 in South Carolina → Every provider in Greenville → Internal Medicine Physician nationwide →
The 8 internal medicine physician records with the nearest ZIP codes
- Stephanie BrowerGreenville, SC 296111912848276
- Kegan Cox, MDGreenville, SC 296111205777562
- Leopoldo Dobronski Jacome, MDGreenville, SC 296111629381637
- Austin FretwellGreenville, SC 296111093440455
- Sydney GandyGreenville, SC 296111740121003
- Beverly Garrison-Stigall, MDGreenville, SC 296111861418824
- Katherine Lumpkin, D.O.Greenville, SC 296111346477254
- Maxwell Pappas, MDGreenville, SC 296111427851880
Common questions
What is Mark Louis Wess, M.D.'s NPI number?
Mark Louis Wess, M.D.'s National Provider Identifier (NPI) is 1861440042, issued on May 4, 2006. An NPI identifies a provider in billing; it is not a license.
Where is Mark Louis Wess, M.D. located?
The NPPES record lists a practice address at 3516 Highway 153, Greenville, SC, 29611. Phone: (864) 729-6626. Providers update this record themselves, so call before visiting.
How can I verify Mark Louis Wess, M.D.'s license?
NPPES lists South Carolina license number 35155, as entered by the provider. Search the South Carolina Board of Medical Examiners at https://verify.llronline.com/LicLookup/Med/Med.aspx?div=22. The NPPES record confirms identity only; the state search shows license status, expiration and public orders.
How much does Mark Louis Wess, M.D. prescribe under Medicare Part D?
In 2024, Mark Louis Wess, M.D. had 5,573 Medicare Part D claims for 779 beneficiaries; the average among internal medicine physician prescribers was 3,176. Part D covers Medicare prescriptions only.
Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.
Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.