NPPES file of Aug 9, 2026

Mary Denise Hughes, MD

Neurology Physician · Greenville, SC

Mary Denise Hughes, MD is a neurology physician with a practice address in Greenville, South Carolina, and NPI 1275643561, issued on Aug 30, 2006. Check the license (South Carolina 30585, as entered in NPPES) on the South Carolina Board of Medical Examiners; the Medicare figures below come from public CMS files.

Record from CMS NPPES, file of Aug 9, 2026 · Medicare files 2024 · method · Verify with CMS →

NPPES recordNPPES file of Aug 9, 2026
1275643561
Name
Mary Denise Hughes
Credential
MD
Primary taxonomy
Neurology Physician 2084N0400X
License numbers
30585 SC
042614 GA
Self-reported in NPPES; status is on the state search
Practice location
52 Bear Dr, Greenville, SC 29605
Phone
(864) 655-4005
Enumerated
Aug 30, 2006
Record last updated
Dec 30, 2024
Fax
(864) 655-4004
Medicaid ID
G42614 SC
Medicare enrollment
Enrolled (PECOS I20151112002476); accepts Medicare assignment
Medical or professional school
University Of Tennessee, Hsc, College Of Medicine, 1989
Telehealth
Offers telehealth (CMS)
Entity
Type 1 · individual
Public record from CMS NPPES (open it on the CMS NPI Registry). Enrollment, assignment, school and telehealth: CMS Doctors and Clinicians file, Aug 2026. A record is not a license: verify it with the state board.
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Also registered at 52 Bear Dr

A shared address usually means a shared clinic or building; it does not show who employs whom.

  1. Charlton Armstrong, M.D.Urology Physician1952330326
  2. Tangela Bass, ACUPUNCTURISTAcupuncturist1992023956
  3. Andrew Bullock, M.D.Urology Physician1194936385
  4. Lynn Curry, ANPAdult Health Nurse Practitioner1285714956
  5. Thomas Hamilton, M.D.Urology Physician1053349555
  6. Michael Mathers, M.D.Urology Physician1679509178

Verify Mary Denise Hughes in five checks

  1. 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
  2. 2LicenseActive license and public ordersSouth Carolina Board of Medical Examiners
    Search for license 30585
    Check the board
  3. 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
  4. 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
  5. 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
Open the South Carolina license search

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72% fewer Medicare Part D claims than the average neurology physician in 2024

390 Medicare Part D claims for 101 beneficiaries, against an average of 1,370 among the 15,005 providers of this specialty who prescribed in Part D. Brand-name drugs were 30% of claims.

  1. Mary Hughes390
  2. Specialty average1,370

Most prescribed

  1. Baclofen32 claims
  2. Botox27 claims
  3. Sertraline Hcl26 claims
  4. Teriflunomide21 claims
  5. Fingolimod19 claims
  6. Dalfampridine Er17 claims

Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.

Industry payments in 2024: $48,792.79

153 payments; by number, the most common kind was food and beverage; the largest payer was Emd Serono, Inc. The 10,858 providers of this specialty with any payment received $8,318.07 on average. Payments are reported by manufacturers, not by the provider, and are not a sign of wrongdoing.

  1. Mary Hughes$48,793
  2. Specialty average$8,318

Source: CMS Open Payments, program year 2024 (openpaymentsdata.cms.gov); average among providers of this specialty with at least one payment.

Bills Medicare through one group practice

  1. Lifestyle Neurology LLCGreenville, SC

Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).

Neurology Physician providers in South Carolina

There are 326 neurology physician records in South Carolina.

Other neurology physician records in South Carolina

  1. Eunice Abrams, M.D.Florence, SC1942598909
  2. John Absher, M.D.Greenville, SC1417949751
  3. Ahmad Abu Qdais, MDCharleston, SC1083346274
  4. Julian Adams, M.D.Columbia, SC1639180946
  5. Robert Adams, MDCharleston, SC1003919911
  6. Nana Boakye Agyeman Badu, MD MPHCharleston, SC1689562910
  7. Amna Ahmed, MDGreer, SC1215788310
  8. Saleh Alhasan, MDRock Hill, SC1912361031
  9. Mohammed Alhatou, M.D.Orangeburg, SC1124057245
  10. Hamid Ali, M.D.Charleston, SC1235751751

Common questions

What is Mary Denise Hughes, MD's NPI number?

Mary Denise Hughes, MD's National Provider Identifier (NPI) is 1275643561, issued on Aug 30, 2006. An NPI identifies a provider in billing; it is not a license.

Where is Mary Denise Hughes, MD located?

The NPPES record lists a practice address at 52 Bear Dr, Greenville, SC, 29605. Phone: (864) 655-4005. Providers update this record themselves, so call before visiting.

How can I verify Mary Denise Hughes, MD's license?

NPPES lists South Carolina license number 30585, as entered by the provider. Search the South Carolina Board of Medical Examiners at https://verify.llronline.com/LicLookup/Med/Med.aspx?div=22. The NPPES record confirms identity only; the state search shows license status, expiration and public orders.

How much does Mary Denise Hughes, MD prescribe under Medicare Part D?

In 2024, Mary Denise Hughes, MD had 390 Medicare Part D claims for 101 beneficiaries; the average among neurology physician prescribers was 1,370. Part D covers Medicare prescriptions only.

Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.

Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.