Melissa Anne Layno Santillan, M.D.
Family Medicine Physician · Cypress, TX
Melissa Anne Layno Santillan, M.D. is a family medicine physician with a practice address in Cypress, Texas, and NPI 1588955405, issued on Apr 26, 2011. Check the license (Texas Q3396, as entered in NPPES) on the Texas Medical Board; the Medicare figures below come from public CMS files.
- Name
- Melissa Anne Layno Santillan
- Credential
- M.D.
- Primary taxonomy
- Family Medicine Physician 207Q00000X
- License numbers
- Q3396 TX
L3477R AL
MD33607 AL
Self-reported in NPPES; status is on the state search - Practice location
- 21214 Northwest Freeway, Cypress, TX 77429
- Phone
- (832) 912-3800
- Enumerated
- Apr 26, 2011
- Record last updated
- Dec 5, 2024
- Entity
- Type 1 · individual
8 nearest family medicine physician records → All 11,119 in Texas → Look up another NPI →
Also registered at 21214 Northwest Freeway
A shared address usually means a shared clinic or building; it does not show who employs whom.
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Verify Melissa Anne Layno Santillan in five checks
- 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
- 2LicenseActive license and public ordersTexas Medical Board
Search for license Q3396Check the board - 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
- 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
- 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
100% fewer Medicare Part D claims than the average family medicine physician in 2024
11 Medicare Part D claims for 11 beneficiaries, against an average of 3,544 among the 117,163 providers of this specialty who prescribed in Part D.
Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.
Melissa Anne Layno Santillan among 11,119 family medicine physician records in Texas
Melissa Anne Layno Santillan, M.D. is one of 11,119 family medicine physician records with a practice address in Texas. 82% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2011, is newer than 64% of them.
- NPI issued2011 · 64% of these records are older, 33% newer
- In a Medicare fileYes · 82% of these records are
- In the CMS Doctors and Clinicians fileNo · 64% of these records are
- Record last updated2024 · 51% of these records were not updated in five years or more
Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 207Q00000X and a Texas practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).
68 family medicine physician records list a practice address in Cypress
They are 68 of the 2,457 NPPES records with a practice address in Cypress, and 11,119 family medicine physician records in Texas.
All 11,119 in Texas → Every provider in Cypress → Family Medicine Physician nationwide →
The 8 family medicine physician records with the nearest ZIP codes
- Asma Ahmad, MDCypress, TX 774291093781353
- Michael Barnard, MDCypress, TX 774291144215369
- Sheriev Boctor, DOCypress, TX 774291013021195
- Sartaj Chatha, M.D.Cypress, TX 774291679893143
- Julius Debroeck, MDCypress, TX 774291023180429
- Alfredo Ermac, M.D.Cypress, TX 774291649268384
- Deanna Haun-Hita, MDCypress, TX 774291962704627
- Linda Holleran, MDCypress, TX 774291962583807
Common questions
What is Melissa Anne Layno Santillan, M.D.'s NPI number?
Melissa Anne Layno Santillan, M.D.'s National Provider Identifier (NPI) is 1588955405, issued on Apr 26, 2011. An NPI identifies a provider in billing; it is not a license.
Where is Melissa Anne Layno Santillan, M.D. located?
The NPPES record lists a practice address at 21214 Northwest Freeway, Cypress, TX, 77429. Phone: (832) 912-3800. Providers update this record themselves, so call before visiting.
How can I verify Melissa Anne Layno Santillan, M.D.'s license?
NPPES lists Texas license number Q3396, as entered by the provider. Search the Texas Medical Board at https://profile.tmb.state.tx.us/Search.aspx. The NPPES record confirms identity only; the state search shows license status, expiration and public orders.
How much does Melissa Anne Layno Santillan, M.D. prescribe under Medicare Part D?
In 2024, Melissa Anne Layno Santillan, M.D. had 11 Medicare Part D claims for 11 beneficiaries; the average among family medicine physician prescribers was 3,544. Part D covers Medicare prescriptions only.
Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.
Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.