NPPES file of Aug 9, 2026

Melissa Ann Destefano, PA-C

Medical Physician Assistant · Lancaster, PA

Melissa Ann Destefano, PA-C is a medical physician assistant with a practice address in Lancaster, Pennsylvania, and NPI 1265461313, issued on Jul 1, 2006. Check the license (Pennsylvania MA053304, as entered in NPPES) with the Pennsylvania board that licenses this profession; the Medicare figures below come from public CMS files.

Record from CMS NPPES, file of Aug 9, 2026 · Medicare files 2024 · method · Verify with CMS →

NPPES recordNPPES file of Aug 9, 2026
1265461313
Name
Melissa Ann Destefano
Credential
PA-C
Primary taxonomy
Medical Physician Assistant 363AM0700X
License number
MA053304 PA
Self-reported in NPPES; status is on the state search
Practice location
2150 Harrisburg Pike, Lancaster, PA 17601
Phone
(717) 396-9167
Enumerated
Jul 1, 2006
Record last updated
Sep 18, 2025
Fax
(717) 396-9064
Medicare enrollment
Enrolled (PECOS I20080605000120); accepts Medicare assignment
Telehealth
Offers telehealth (CMS)
Entity
Type 1 · individual
Public record from CMS NPPES (open it on the CMS NPI Registry). Enrollment, assignment, school and telehealth: CMS Doctors and Clinicians file, Aug 2026. A record is not a license: verify it with the state board.
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Also registered at 2150 Harrisburg Pike

A shared address usually means a shared clinic or building; it does not show who employs whom.

  1. Jennie Corinne Baublitz Brenenborg, DOPain Medicine Physician1538119854
  2. Rupak Bhuyan, M.DOphthalmology Physician1609363829
  3. Lynn CollinsRegistered Dietitian1437928835
  4. Allison Crowell, MDNeurology Physician1114312568
  5. Ellen Depoy, MDNeurology Physician1992230726
  6. Signe Fink, MPTPhysical Therapist1477730455

Verify Melissa Ann Destefano in five checks

  1. 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
  2. 2LicenseActive license and public ordersWhich Pennsylvania board licenses this profession
    Search for license MA053304
    Check the board
  3. 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
  4. 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
  5. 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
Find the Pennsylvania license search

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2.1 times the Medicare Part D claims of the average medical physician assistant in 2024

2,428 Medicare Part D claims for 392 beneficiaries, against an average of 1,148 among the 23,801 providers of this specialty who prescribed in Part D.

  1. Melissa Destefano2,428
  2. Specialty average1,148

Most prescribed

  1. Gabapentin217 claims
  2. Venlafaxine Hcl Er176 claims
  3. Levetiracetam161 claims
  4. Pregabalin149 claims
  5. Lamotrigine74 claims
  6. Topiramate70 claims

Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.

Industry payments in 2024: $248.51

5 payments; by number, the most common kind was food and beverage; the largest payer was TG Therapeutics, Inc. The 16,165 providers of this specialty with any payment received $1,055.00 on average. Payments are reported by manufacturers, not by the provider, and are not a sign of wrongdoing.

  1. Melissa Destefano$248.51
  2. Specialty average$1,055.00

Source: CMS Open Payments, program year 2024 (openpaymentsdata.cms.gov); average among providers of this specialty with at least one payment.

Bills Medicare through one group practice

  1. Lancaster General Medical GroupLancaster, PA

Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).

92 medical physician assistant records list a practice address in Lancaster

They are 92 of the 5,378 NPPES records with a practice address in Lancaster, and 3,897 medical physician assistant records in Pennsylvania.

Other medical physician assistant records in Pennsylvania

  1. Savannah Aanderud, PA-CErie, PA1811625437
  2. Kathryn Abadi, PA-CWellsboro, PA1407034077
  3. Michael Abbott, PA-CPittsburgh, PA1942815915
  4. Patricia Abbott, PA-CPhiladelphia, PA1316011018
  5. Paul AbbottButler, PA1114903093
  6. Bashera Abdul-Hadi, PA-CPhiladelphia, PA1174570329
  7. Danielle Abel, PA-CSewickley, PA1255751731
  8. Nicallina Abel, PA-CTrevose, PA1043862592
  9. Maria Abraham, PA-CBethel Park, PA1124176821
  10. Sarah Abraham, PA-CPittsburgh, PA1518293448

Common questions

What is Melissa Ann Destefano, PA-C's NPI number?

Melissa Ann Destefano, PA-C's National Provider Identifier (NPI) is 1265461313, issued on Jul 1, 2006. An NPI identifies a provider in billing; it is not a license.

Where is Melissa Ann Destefano, PA-C located?

The NPPES record lists a practice address at 2150 Harrisburg Pike, Lancaster, PA, 17601. Phone: (717) 396-9167. Providers update this record themselves, so call before visiting.

How can I verify Melissa Ann Destefano, PA-C's license?

NPPES lists Pennsylvania license number MA053304, as entered by the provider. Search the Pennsylvania board that licenses this profession; the NPPES record confirms identity only.

How much does Melissa Ann Destefano, PA-C prescribe under Medicare Part D?

In 2024, Melissa Ann Destefano, PA-C had 2,428 Medicare Part D claims for 392 beneficiaries; the average among medical physician assistant prescribers was 1,148. Part D covers Medicare prescriptions only.

Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.

Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.