NPPES file of Aug 9, 2026

Orlando M. Leon Santiago, MD

General Practice Physician · Guaynabo, PR

Orlando M. Leon Santiago, MD is a general practice physician with a practice address in Guaynabo, Puerto Rico, and NPI 1659930105, issued on Jun 9, 2019. Check the license (Puerto Rico 21382, as entered in NPPES) with the Puerto Rico board that licenses this profession; the Medicare figures below come from public CMS files.

Record from CMS NPPES, file of Aug 9, 2026 · Medicare files 2024 · method · Verify with CMS →

NPPES recordNPPES file of Aug 9, 2026
1659930105
Name
Orlando M. Leon Santiago
Credential
MD
Primary taxonomy
General Practice Physician 208D00000X
License number
21382 PR
Self-reported in NPPES; status is on the state search
Practice location
C6 Calle Yagrumo, Guaynabo, PR 00969
Phone
(787) 241-6128
Enumerated
Jun 9, 2019
Record last updated
Jul 19, 2019 (not updated in 7 years: call before relying on the address or phone)
Medicare enrollment
Enrolled (PECOS I20191219002650); accepts Medicare assignment
Medical or professional school
University Of Puerto Rico School Of Medicine, 2014
Entity
Type 1 · individual
Public record from CMS NPPES (open it on the CMS NPI Registry). Enrollment, assignment, school and telehealth: CMS Doctors and Clinicians file, Aug 2026. A record is not a license: verify it with the state board.
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Also registered at C6 Calle Yagrumo

A shared address usually means a shared clinic or building; it does not show who employs whom.

  1. Zaida Santiago Vega, PTPhysical Therapist1740240217

Verify Orlando M. Leon Santiago in five checks

  1. 1IdentityNPI record in CMS NPPESNPI lookupConfirmed in NPPES
  2. 2LicenseActive license and public ordersWhich Puerto Rico board licenses this profession
    Search for license 21382
    Check the board
  3. 3Other statesLicenses and actions elsewhereDocInfo (FSMB)Not checked
  4. 4ExclusionsMedicare and Medicaid bansHHS-OIG exclusion listNot checked
  5. 5CertificationBoard certificationABMS AOA NCCPA AANPNot checked
Find the Puerto Rico license search

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88% fewer Medicare Part D claims than the average general practice physician in 2024

356 Medicare Part D claims for 261 beneficiaries, against an average of 3,030 among the 8,395 providers of this specialty who prescribed in Part D.

  1. Orlando Leon Santiago356
  2. Specialty average3,030

Most prescribed

  1. Diclofenac Sodium70 claims
  2. Orphenadrine Citrate Er45 claims
  3. Prednisolone Sodium Phosphate41 claims
  4. Azithromycin37 claims
  5. Ciprofloxacin Hcl18 claims
  6. Famotidine13 claims

Source: CMS Medicare Part D Prescribers by Provider and Drug, 2024 (data.cms.gov). Part D covers prescriptions for Medicare patients only; drugs with fewer than 11 claims are not published.

Bills Medicare through 2 group practices

  1. ER Specialized Care LLCHato Rey, PR
  2. Salud Integral EN LA Montana IncOrocovis, PR

Source: CMS Doctors and Clinicians National Downloadable File (the group practices a clinician bills Medicare through) (data.cms.gov).

Orlando M. Leon Santiago among 4,170 general practice physician records in Puerto Rico

Orlando M. Leon Santiago, MD is one of 4,170 general practice physician records with a practice address in Puerto Rico. 78% of them appear in a Medicare file (Part D prescribing, MIPS, Open Payments or Medicare group billing); this one does. Its NPI, issued in 2019, is newer than 69% of them.

  • NPI issued2019 · 69% of these records are older, 27% newer
  • In a Medicare fileYes · 78% of these records are
  • In the CMS Doctors and Clinicians fileYes · 29% of these records are
  • Graduated2014 · median 2004 among the 1,228 with a school on file
  • Record last updated2019 · 58% of these records were not updated in five years or more

Source: CMS NPPES, file of Aug 9, 2026, every record with primary taxonomy 208D00000X and a Puerto Rico practice address; Medicare files: CMS Part D Prescribers 2024, MIPS 2023, Open Payments 2024, Doctors and Clinicians (data.cms.gov).

97 general practice physician records list a practice address in Guaynabo

They are 97 of the 2,143 NPPES records with a practice address in Guaynabo, and 4,170 general practice physician records in Puerto Rico.

The 8 general practice physician records with the nearest ZIP codes

  1. Maribel Acevedo, MDGuaynabo, PR 009691699743864
  2. Maria Gonzalez, M.D.Guaynabo, PR 009691588692396
  3. Aixa Mariani, MDGuaynabo, PR 009691194708891
  4. Joaquin Ng, MD.Guaynabo, PR 009691679538391
  5. Osvaldo Niebla Diaz, M.D.Guaynabo, PR 009691174550131
  6. Petra Ortiz, M.D.Guaynabo, PR 009691609970094
  7. Yolanda Pagan Rivera, MDGuaynabo, PR 009691205817400
  8. Jose Pastrana, MDGuaynabo, PR 009691861462186

Common questions

What is Orlando M. Leon Santiago, MD's NPI number?

Orlando M. Leon Santiago, MD's National Provider Identifier (NPI) is 1659930105, issued on Jun 9, 2019. An NPI identifies a provider in billing; it is not a license.

Where is Orlando M. Leon Santiago, MD located?

The NPPES record lists a practice address at C6 Calle Yagrumo, Guaynabo, PR, 00969. Phone: (787) 241-6128. Providers update this record themselves, so call before visiting.

How can I verify Orlando M. Leon Santiago, MD's license?

NPPES lists Puerto Rico license number 21382, as entered by the provider. Search the Puerto Rico board that licenses this profession; the NPPES record confirms identity only.

How much does Orlando M. Leon Santiago, MD prescribe under Medicare Part D?

In 2024, Orlando M. Leon Santiago, MD had 356 Medicare Part D claims for 261 beneficiaries; the average among general practice physician prescribers was 3,030. Part D covers Medicare prescriptions only.

Source: CMS National Plan and Provider Enumeration System (NPPES), file of Aug 9, 2026 (NPPES files on CMS.gov); NUCC Health Care Provider Taxonomy. Medicare files from data.cms.gov. An NPI identifies who bills; it is not a license.

Figures on PlainDoctor are read from the federal files each page names (CMS NPPES, Medicare Part D, MIPS, Open Payments; the HHS-OIG exclusion list only as counts) and from Census population estimates, with the file date shown beside them. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of Aug 9, 2026.