REBECCA HOLDREN, M.D. appears in the CMS NPPES registry as a Pain Medicine (Physical Medicine & Rehabilitation) Physician provider holding M.D. credentials at 111 DOCTORS DR, GREENVILLE, SC, 29605, with a listed phone of (864) 797-7100. NPI 1245217322 was issued on 12/29/2005. Because NPPES data is self-reported by the provider and refreshed monthly, the address, phone, and specialty reflect what HOLDREN most recently submitted to CMS rather than a vetted directory listing, which is why patients should always confirm the practice is still at this location before scheduling.

Medicare Part D records for calendar year 2023 show 6,039 prescription claims written by this provider, covering 589 Medicare beneficiaries and totaling roughly $703K in drug spend, split 10% brand-name and 90% generic by claim count, with an opioid prescribing rate of 45.7%. These figures capture only Medicare Part D — commercial insurance, Medicaid, and cash-pay prescriptions are not included, and any drug-beneficiary cell under 11 is suppressed by CMS for patient privacy.

Pain Medicine (Physical Medicine & Rehabilitation) Physician is a narrow specialty nationwide, with 1,626 enrolled providers across 50 states and an average of 1,401 Part D claims per prescriber, so the context for interpreting these metrics differs meaningfully from a primary-care baseline. Important: PlainDoctor is a directory of publicly available government data, not medical advice, a malpractice database, or a quality rating. Inclusion here does not imply a recommendation, and absence of complaints or sanctions on this page does not mean none exist — always verify credentials through the NPPES NPI Registry, your state medical board, and the ABMS or AOA before making healthcare decisions.