William Nienaber, MD appears in the CMS NPPES registry as a Cardiovascular Disease Physician provider holding MD credentials at 211 SAINT FRANCIS DR STE 15, Cape Girardeau, MO, 63703, with a listed phone of (573) 331-3333. NPI 1720296940 was issued on 05/20/2007. Because NPPES data is self-reported by the provider and refreshed monthly, the address, phone, and specialty reflect what Nienaber most recently submitted to CMS rather than a vetted directory listing, which is why patients should always confirm the practice is still at this location before scheduling.

Medicare Part D records for calendar year 2023 show 3,270 prescription claims written by this provider, covering 366 Medicare beneficiaries and totaling roughly $436K in drug spend, split 17% brand-name and 83% generic by claim count. These figures capture only Medicare Part D — commercial insurance, Medicaid, and cash-pay prescriptions are not included, and any drug-beneficiary cell under 11 is suppressed by CMS for patient privacy.

Cardiovascular Disease Physician is a mid-sized specialty nationwide, with 24,795 enrolled providers across 54 states and an average of 3,033 Part D claims per prescriber, so the context for interpreting these metrics differs meaningfully from a primary-care baseline. Important: PlainDoctor is a directory of publicly available government data, not medical advice, a malpractice database, or a quality rating. Inclusion here does not imply a recommendation, and absence of complaints or sanctions on this page does not mean none exist — always verify credentials through the NPPES NPI Registry, your state medical board, and the ABMS or AOA before making healthcare decisions.