The CMS National Plan and Provider Enumeration System currently lists 2,235 Internal Medicine Physician providers with a primary practice address in South Carolina, all registered under the Internal Medicine NUCC taxonomy branch. Each clinician on this roster selected Internal Medicine Physician as their primary taxonomy at NPI enrollment — a self-reported classification that is updated whenever the provider files a correction with CMS. The count excludes organizations (group practices, hospitals, clinics operate under separate NPIs) and excludes providers who chose a different primary specialty even if they practice Internal Medicine Physician part-time.

At 2,235 enrolled providers, Internal Medicine Physician in South Carolina is a mid-volume market — that matters for search-radius decisions, because patients in South Carolina outside the largest metros often need to broaden to adjacent cities to find a local Internal Medicine Physician clinician. The directory below is paginated 50 providers at a time (45 pages total) and is sorted alphabetically by last name, so scanning for a specific practice usually goes faster than scrolling; on the provider detail page you'll find the full NPPES record including address, phone, credentials, and any published Medicare Part D prescribing activity for 2023.

Before contacting anyone on this list, verify the practice is still at the address shown — NPPES refreshes monthly, but providers who have relocated, retired, or changed employers may not have filed an NPI update yet. Important: PlainDoctor is a directory of publicly available CMS government data covering Internal Medicine Physician providers in South Carolina, not a quality ranking, a board-certification verifier, or medical advice. Always confirm credentials through the NPPES NPI Registry, the South Carolina medical board, and — where relevant — the ABMS, AOA, or the specialty's primary certifying body before making any clinical decision. Nothing on this page substitutes for a conversation with a licensed clinician.