NPPES file of Aug 9, 2026

Opioid prescribers by state, 2024: Mississippi highest at 67.05%, Puerto Rico lowest at 45.82%

Share of Medicare Part D prescribers who wrote at least one opioid in 2024, from CMS: Mississippi 67.05%, Puerto Rico 45.82%, all prescribers 57.09% (808,192 of 1,415,649).

Research period:

Research question

In each state, what share of the clinicians who prescribe under Medicare Part D wrote at least one opioid prescription in 2024, and how large a part of all their Part D prescriptions were opioids? The share of prescribers measures how widely opioids are prescribed across a state's clinicians; the prescribing rate measures how much of the prescribing they are.

Methodology

Every figure comes from CMS's Medicare Part D Opioid Prescribing Rates by Geography file, released in June 2026: the state and national totals. CMS counts each state's Part D prescribers and those with at least one opioid claim before it suppresses small cells, so these counts include the prescribers with 1 to 10 opioid claims whose values are blank in the per-prescriber file. The share is opioid prescribers divided by prescribers; the prescribing rate is CMS's opioid claims per 100 Part D claims. The 52 states and territories with 1,000 or more Part D prescribers are ranked; Virgin Islands, Guam and Northern Mariana Islands have fewer and are left out of the ranking.

Findings

Mississippi is highest: 67.05% of its prescribers wrote an opioid

Of the 10,877 clinicians who prescribed under Medicare Part D in Mississippi in 2024, 7,293 wrote at least one opioid prescription, 67.05%. CMS Medicare Part D Opioid Prescribing Rates by Geography, 2024 Across all 1,415,649 Part D prescribers the share was 57.09% (808,192), and 34 of the 52 ranked jurisdictions were above it. The next four were Utah (65.59%), Oregon (65.15%), Montana (64.88%), Kansas (64.65%).

Highest share of prescribers writing an opioid, 2024

Share of Part D prescribers with at least one opioid claim

1. Mississippi67.05%2. Utah65.59%3. Oregon65.15%4. Montana64.88%5. Kansas64.65%

Puerto Rico is lowest at 45.82%

Of the 11,209 Part D prescribers in Puerto Rico, 5,136 wrote at least one opioid, 45.82%, 21.23 percentage points below Mississippi. CMS Medicare Part D Opioid Prescribing Rates by Geography, 2024 The other four lowest were New York (47.33%), Florida (51.24%), New Jersey (52.79%), District of Columbia (52.86%).

Lowest share of prescribers writing an opioid, 2024

Share of Part D prescribers with at least one opioid claim

Puerto Rico45.82%New York47.33%Florida51.24%New Jersey52.79%District of Columbia52.86%

Opioids as a share of all prescriptions: Alabama highest at 5.19 per 100 claims

Nationally, opioids were 3.52 of every 100 Part D claims in 2024, 0.89 points fewer than five years earlier. CMS Medicare Part D Opioid Prescribing Rates by Geography, 2024 By this measure Alabama (5.19), Utah (5.10) and Idaho (5.01) were highest. A state can rank high on one measure and not the other: Mississippi leads on the share of prescribers at a rate of 4.06.

California, with the most prescribers, ranks 39 of 52 at 55.87%

California had 143,181 Part D prescribers in 2024, the most of any state; 79,990 of them wrote at least one opioid, 55.87%. The share is a proportion of a state's own prescribers, so a large state has no advantage in it.

The national share since 2013

In 2013, 77.68% of Part D prescribers wrote an opioid and opioids were 5.82 of every 100 claims; in 2024 the figures were 57.09% and 3.52.

Every ranked jurisdiction

RankStatePart D prescribersWrote an opioidShareOpioid claims per 100
1Mississippi10,8777,29367.05%4.06
2Utah11,6567,64565.59%5.10
3Oregon19,55812,74265.15%4.68
4Montana5,0253,26064.88%4.37
5Kansas11,8287,64764.65%4.13
6Michigan47,22130,43064.44%4.21
7Nebraska8,4865,44464.15%3.36
8Colorado24,60315,77564.12%4.65
9Idaho7,7064,93364.02%5.01
10South Dakota4,1082,62964.00%3.46
11North Dakota3,5972,30163.97%2.97
12North Carolina45,28928,65663.27%4.16
13Wyoming2,2111,39663.14%4.58
14Minnesota26,27516,34262.20%3.04
15Wisconsin26,02416,18362.18%3.25
16Louisiana20,78712,89362.02%4.18
17Arkansas12,1547,51561.83%4.72
18Indiana26,77216,50261.64%4.24
19Tennessee29,82518,28161.29%4.38
20Alaska3,1151,90361.09%3.82
21South Carolina22,19013,50060.84%4.03
22Ohio54,55332,90960.32%3.23
23Washington33,33519,94759.84%4.24
24Maine7,3794,41359.80%3.30
25Georgia37,93622,61159.60%4.32
26Virginia33,52819,81759.11%3.29
27Oklahoma14,4418,50058.86%4.76
28Hawaii5,0412,93158.14%2.75
29Vermont3,0181,75057.99%3.20
30Illinois53,80431,14057.88%3.14
31Iowa13,4357,76757.81%3.15
32New Mexico8,3974,82757.48%3.85
33Rhode Island5,9273,40557.45%2.43
34New Hampshire7,2504,14657.19%2.97
35Delaware4,4702,55057.05%3.66
36West Virginia8,6864,94556.93%3.19
37Texas95,71153,96956.39%3.62
38Maryland27,00315,09755.91%3.74
39California143,18179,99055.87%3.29
40Arizona30,58717,07055.81%4.04
41Massachusetts40,62122,46355.30%2.71
42Nevada10,7285,86754.69%4.64
43Pennsylvania65,79335,93854.62%2.92
44Missouri26,14514,08453.87%3.94
45Kentucky19,44110,46353.82%4.46
46Alabama18,3219,78353.40%5.19
47Connecticut20,10510,69553.20%2.77
48District of Columbia5,2522,77652.86%2.61
49New Jersey37,31519,70052.79%2.42
50Florida97,24449,82951.24%3.52
51New York106,10350,21747.33%2.03
52Puerto Rico11,2095,13645.82%0.59

What this analysis cannot tell us

Both measures count Medicare Part D prescriptions only, not Medicaid, commercial insurance or cash prescriptions, and neither says whether a prescription was appropriate. The share counts whether a clinician wrote any opioid, not how many or in what doses. The prescriber's state is the state CMS assigns, which can differ from where the patients live.

Sources